Multiple astrocytic hamartomas in patients with tuberous sclerosis
https://doi.org/10.52485/19986173_2023_4_113
Abstract
Tuberous sclerosis is a multisystem lesion of the human body, consisting in the formation of benign neoplasms in various organs and systems. The specificity of the disease is associated with genetic mutations in the TSC – 1 and TSC – 2 genes, which are suppressors of tumor growth. Diagnosis of tuberous sclerosis in early childhood is extremely difficult and often these patients are observed and treated with a diagnosis of epilepsy, mental retardation and numerous neoplasms of various tissues of organs and systems.
The presented article shows two clinical cases of tuberous sclerosis with ophthalmological manifestations of this pathology. The presence of astrocytic hamartomas, which are the primary diagnostic criterion of the disease, makes it necessary to conduct full ophthalmic examination in time in order to identify the disease.
About the Authors
S. I. Zhukova
Irkutsk branch of S. Fyodorov “Eye microsurgery” Federal State Institution of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
664033, Irkutsk, Lermontov str., 337
D. Yu. Samsonov
Irkutsk branch of S. Fyodorov “Eye microsurgery” Federal State Institution of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
664033, Irkutsk, Lermontov str., 337
К. А. Chanchikov
Irkutsk State Medical Academy of Postgraduate Education - a branch of Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
664049, Irkutsk, Yubileyny, 100
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Review
For citations:
Zhukova S.I., Samsonov D.Yu., Chanchikov К.А. Multiple astrocytic hamartomas in patients with tuberous sclerosis. Transbaikalian Medical Bulletin. 2023;(4):113-118. (In Russ.) https://doi.org/10.52485/19986173_2023_4_113
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