WILSON-KONOVALOV DISEASE IN CHILDREN: MODERN CONCEPTS AND CLINICAL CASE
https://doi.org/10.52485/19986173_2022_2_106
Abstract
The article summarizes the literature data on a rare pathology – Wilson disease in children. The review cites the case of the personal clinical observation of the complicated diagnosis and successful treatment of a girl with this disease. In the patient the disease debuted as hepatitis with the detection of Ebstein-Barr viruses and herpes type 6. The persisting syndrome of cytolysis after antiviral therapy necessitated the differential diagnosis of non-infectious liver pathology. Identified violations of copper metabolism, low levels of ceruloplasmin, molecular genetic study made it possible to clarify the diagnosis and prescribe pathogenetic treatment. The presented case complements the data available in the literature on Wilson's disease.
About the Authors
E. V. Luzina
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
N. N. Borovik
Regional Children's Clinical Hospital
Russian Federation
Russian Federation
20 Novobulvarnaya Street, Chita, 672027
T. V. Kalinkina
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
S. A. Chavanina
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
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Review
For citations:
Luzina E.V., Borovik N.N., Kalinkina T.V., Chavanina S.A. WILSON-KONOVALOV DISEASE IN CHILDREN: MODERN CONCEPTS AND CLINICAL CASE. Transbaikalian Medical Bulletin. 2022;(2):106-113. (In Russ.) https://doi.org/10.52485/19986173_2022_2_106
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