IDIOPATHIC AUTOIMMUNE ENCEPHALITIS WITH ANTIBODIES TO NMDA RECEPTORS
https://doi.org/10.52485/19986173_2022_2_99
Abstract
Idiopathic autoimmune encephalitis with antibodies to NMDA receptors (EA to NMDAR) is a severe disease of the nervous system characterized by a variety of neuropsychiatric pathology and an involvement of neurotransmitter systems. Due to the wide distribution of the glutamatergic system in the central nervous system, the disease has a severe course, prominent psychotic symptoms with polymorphic neurological pathology. The predominance of acute psychosis at the onset, a diverse clinical picture with a low diagnostic value of neuroimaging (MRI) causes difficulties in establishing a diagnosis and prescribing early pathogenetic therapy.
The article describes a clinical case of EA to NMDAr in a child that arose subacutely and manifested itself as severe mental disorders with further neurological disorders. Given the severity of mental disorders in a patient in childhood age, the rarity of this pathology, the statement of the diagnosis was accompanied by certain difficulties.
About the Authors
Yu. A. Shirshov
Chita State Medical Academy
Russian Federation
Russian Federation
39 A Gorkogo str., Chita, 672000
A. Yu. Ma-Van-de
Chita State Medical Academy
Russian Federation
Russian Federation
39 A Gorkogo str., Chita, 672000
N. A. Marueva
Chita State Medical Academy
Russian Federation
Russian Federation
39 A Gorkogo str., Chita, 672000
A. D. Baldanshirieva
Chita State Medical Academy
Russian Federation
Russian Federation
39 A Gorkogo str., Chita, 672000
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Review
For citations:
Shirshov Yu.A., Ma-Van-de A.Yu., Marueva N.A., Baldanshirieva A.D. IDIOPATHIC AUTOIMMUNE ENCEPHALITIS WITH ANTIBODIES TO NMDA RECEPTORS. Transbaikalian Medical Bulletin. 2022;(2):99-105. (In Russ.) https://doi.org/10.52485/19986173_2022_2_99
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