RHYTHM DISTURBANCES AND ELECTROPHYSIOLOGICAL PARAMETERS OF THE HEART IN PATIENTS WITH POLYCYTHEMIA VERA
https://doi.org/10.52485/19986173_2022_1_94
Abstract
The aim of the research. To study the features of cardiac arrhythmias, heart rate variability parameters, QT interval duration and late ventricular potentials in patients with true polycythemia.
Materials and methods. In 63 patients with true polycythemia of stage I-IIB and 52 healthy individuals, cardiac arrhythmias, heart rate variability parameters, QT interval duration and late ventricular potentials were studied by daily ECG monitoring. Statistical data processing was carried out using Statistica 25.0.
Results. In patients with polycythemia vera, against the background of a decrease in overall heart rate variability (22=15.16, df=2, p<0.001) and a decrease in parasympathetic activity (χ2=7.29, df=1, p=0.007), a tendency to lengthen the maximum corrected QT interval (p=0.09), frequent ventricular extrasystoles were recorded 18 times more often (U=364.0, p=0.047), polymorphic extrasystoles (χ2=33.62, df=4, p<0.001). Paired ventricular extrasystoles were detected only in the group of patients (in 4.8%). Late ventricular potentials were 6.6 times more often registered in the group of patients with polycythemia vera compared to the controls (χ2=9.25, df=1, p=0.002).
Conclusion. In patients with polycythemia vera, more severe cardiac arrhythmias were detected. Violations of the electrophysiological parameters of the heart can serve as markers of dangerous ventricular arrhythmias in patients with true polycythemia.
About the Authors
P. O. Gorskij
Chita State Medical Academy
Russian Federation
Russian Federation
39А Gorky Str., Chita, 672000
E. V. Goncharova
Chita State Medical Academy
Russian Federation
Russian Federation
39А Gorky Str., Chita, 672000
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Review
For citations:
Gorskij P.O., Goncharova E.V. RHYTHM DISTURBANCES AND ELECTROPHYSIOLOGICAL PARAMETERS OF THE HEART IN PATIENTS WITH POLYCYTHEMIA VERA. Transbaikalian Medical Bulletin. 2022;(1):94-103. (In Russ.) https://doi.org/10.52485/19986173_2022_1_94
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