PREDICTION OF AORTIC EVENTS BASED ON THE RESULTS OF HISTOLOGICAL EXAMINATION DURING TRAUMATIC DISSECTION OF THE BRACHIOCEPHALIC ARTERIES

Abstract

Objective. To retrospectively present histologic preparations from patients who had a history of traumatic BCA dissection and subsequently underwent aortic surgery for aortic dissection, aortic aneurysm.
Materials and Methods. In this case series, we present retrospective data of histologic and genetic study of lifetime biological material from patients who had suffered traumatic detachment of the orifices of brachiocephalic arteries but did not have a verified diagnosis of aortic dissection, aortic aneurysm.
Results. The histologic study of the biomaterial obtained at the stage of non-radical correction of cerebral ischemia revealed histologic predictors of further development of aortic events - aortic dilatation with and without development of aortic regurgitation.
Conclusions. This series of clinical cases raises the problem of indications for radical correction of the malformation, determination of histologic predictors of aortic events, revision of the criteria for the diagnosis of “aortic dissection” – consideration of such factors as laminar necrosis of the aortic wall, genetic markers associated with the development of aortic events may be useful in improving the long-term results of management of patients with type A aortic dissection.