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COMPARATIVE ANALYSIS OF QUALITY OF LIFE IN HEALTHY SUBJECTS AND PATIENTS WITH HYPERTENSION USING SF-36 HEALTH STATUS SURVEY QUESTIONNAIRE

https://doi.org/10.52485/19986173_2025_3_63

Abstract

The aim of the research. A comparative analysis of quality of life in conditionally healthy individuals and patients with arterial hypertension using the SF-36 questionnaire.
Materials and methods. The exploration included 525 respondents (349 women and 176 men) aged 18 to 89 years, residing in the Sakhalin Oblast between 2022 and 2023. Among them were 318 conditionally healthy individuals and 207 patients with arterial hypertension. The methodological novelty consisted in the combined application of the SF-36 questionnaire and the Myunsterberg test, which enabled a comprehensive assessment of both physical and mental health, as well as attention concentration levels. Statistical analysis was performed using RStudio, with the Mann–Whitney U test, Kruskal–Wallis test, and Bonferroni correction. Spearman’s rank correlation was used to analyze relationships between variables.
Results. The comparative analysis revealed statistically significant differences between conditionally healthy people and patients with arterial hypertension in terms of physical and psychological components of health (p = 0,045 and p = 0,005, respectively). Patients with hypertension had higher pain intensity (p = 0,0041) and decreased concentration (p = 0,016). In women with hypertension, the indicators of physical and emotional functioning were lower than in men (p < 0,05). No significant sex differences were found in the group of healthy individuals. Correlations between health components have also been established, which differ in men and women with hypertension.
Conclusion. The conducted exploration demonstrated that arterial hypertension adversely affects quality of life, impairing both physical and psychological parameters, particularly in women. The identified differences underscore the importance of comprehensive health assessment accounting for gender-specific characteristics. The application of the SF-36 questionnaire enabled precise documentation of key changes related to pain, physical limitations, and emotional status. These findings hold practical value for individualizing treatment approaches, developing prevention strategies, and designing targeted programs aimed at enhancing quality of life and improving health outcomes in patients with arterial hypertension.

About the Authors

E. V. Markelova
Pacific State Medical University
Russian Federation

Markelova E.V., Doctor of Medical Sciences, Professor, Head of the Department of Normal and Pathological Physiology

2 Ostryakova аv., Vladivostok, 690002



M. Z. Ermolickaja
Institute of Automation and Control Processes of the Far Eastern Branch of the Russian Academy of Sciences
Russian Federation

Ermolickaja M.Z., Candidate of Biological Sciences, Associate Professor; Senior Researcher of the Laboratory of Information, Analytical and Control Systems and Technologies

5 Radio St., Vladivostok, 690041



S. V. Knysh
Pacific State Medical University
Russian Federation

Knysh S.V., Candidate of Medical Sciences, Associate Professor of the Department of Normal and Pathological Physiology

2 Ostryakova аv., Vladivostok, 690002



N. S. Chepurnova
Pacific State Medical University
Russian Federation

Chepurnova N.S., Candidate of Medical Sciences, Associate Professor of the Department of Normal and Pathological Physiology

2 Ostryakova аv., Vladivostok, 690002



M. A. Visjagina M
Pacific State Medical University
Russian Federation

Visjagina M.A., Assistant Professor of the Department of Normal and Pathological Physiology

2 Ostryakova аv., Vladivostok, 690002



G. S. Nadezhdin
Pacific State Medical University
Russian Federation

Nadezhdin G.S., 3rd year student of the medical faculty

2 Ostryakova аv., Vladivostok, 690002



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Markelova E.V., Ermolickaja M.Z., Knysh S.V., Chepurnova N.S., Visjagina M M.A., Nadezhdin G.S. COMPARATIVE ANALYSIS OF QUALITY OF LIFE IN HEALTHY SUBJECTS AND PATIENTS WITH HYPERTENSION USING SF-36 HEALTH STATUS SURVEY QUESTIONNAIRE. Transbaikalian Medical Bulletin. 2025;(3):63-72. (In Russ.) https://doi.org/10.52485/19986173_2025_3_63

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