ПАТОГЕНЕЗ, ДИАГНОСТИКА И ЛЕЧЕНИЕ ОСТРОГО ПОЧЕЧНОГО ПОВРЕЖДЕНИЯ У ПАЦИЕНТОВ С КОРОНАВИРУСНОЙ ИНФЕКЦИЕЙ COVID-19

В обзорной статье представлен анализ научных статей, индексируемых в базах данных PubMed и Web of Science, посвященных патофизиологическим и клиническим особенностям острого почечного повреждения у пациентов с новой коронавирусной инфекцией. Наряду с прямым повреждающим воздействием вируса SARS-CoV-2 на почки и системным последствием вирусной инфекции существуют общие повреждающие факторы острого почечного повреждения для всех критических состояний. Данные о прямом повреждающем воздействии вируса и системном последствии вирусной инфекции противоречивы и требуют дальнейших исследований. Гиповолемия часто встречается на ранних стадиях COVID-19, поэтому экстренное введение жидкости имеет решающее значение для профилактики и лечения острого почечного повреждения у пациентов с новой коронавирусной инфекцией. Оптимизация волемического объема с целью профилактики и предотвращения прогрессирования ОПП до тяжелой степени, требующей проведения заместительной почечной терапии, приобретает особую значимость при ограничении ресурсов в условиях пандемии.

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