Cryptococcosis with bone marrow during hiv infection in the AIDS stage: problems of differential diagnosise
https://doi.org/10.52485/19986173_2023_3_132
Abstract
Cryptococcus is increasingly regarded as a pathogen with a growing number of clinically manifest cases of acquired immunodeficiency syndrome. Usually cryptococcosis is manifested by damage to the lungs, central nervous system or skin. Cases of cryptococcosis with a description of bone marrow lesions are few. A case of generalized cryptococcal lesion in an HIV-infected patient with pronounced splenomegaly and generalized lymphadenopathy is described. The initial diagnosis was established on the basis of microscopy of bone marrow and confirmed by PCR study. The problems of diagnosis of cryptococcosis and differential diagnosis with other infectious lesions of the hematopoietic organs with the detection of pathogens by microscopy of bone marrow are discussed.
About the Authors
Ya. B. Khovaeva
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
S. B. Lyapustin
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
N. A. Sulimova
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
E. I. Voronova
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
N. P. Moiseenko
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
T. N. Titova
Bashkir State Medical University
Russian Federation
Russian Federation
3 Lenin str., Ufa, 450008
A. Zh. Gil'manov
Bashkir State Medical University
Russian Federation
Russian Federation
3 Lenin str., Ufa, 450008
D. Yu. Sosnin
Е.А. Vagner Perm State Medical University
Russian Federation
Russian Federation
26 Petropavlovskaya str., Perm, 614990
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Review
For citations:
Khovaeva Ya.B., Lyapustin S.B., Sulimova N.A., Voronova E.I., Moiseenko N.P., Titova T.N., Gil'manov A.Zh., Sosnin D.Yu. Cryptococcosis with bone marrow during hiv infection in the AIDS stage: problems of differential diagnosise. Transbaikalian Medical Bulletin. 2023;(3):132-140. (In Russ.) https://doi.org/10.52485/19986173_2023_3_132
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