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Impact of a novel coronavirus infection experienced during pregnancy on perinatal outcomes

https://doi.org/10.52485/19986173_2023_3_118

Abstract

Since the beginning of the COVID-19 pandemic, there have been reports about the peculiarities of the course of a new coronavirus infection in a special group of patients - pregnant women. Physiological, immunological changes in the pregnant woman's body lead to the transformation of innate and adaptive immune responses from an inflammatory phenotype to an anti-inflammatory one, suppressing fetal immune rejection reactions and contributing to the passive transmission of maternal antibodies to the fetus. Currently, there is evidence of possible vertical transmission of a new coronavirus infection from mother to fetus and the impact of SARS-CoV2 on the fetus on the thrombogenic orientation of its hemostasis, with the development of adverse outcomes. Literature review and clinical case of an unfavorable perinatal outcome of a COVID-19 infection during pregnancy with the development of hemostasis disorder in a newborn are presented.

About the Authors

A. V. Ignatyeva
Chita State Medical Academy
Russian Federation

39A Gorky str., Chita, 672000



V. V. Kocherova
Chita State Medical Academy
Russian Federation

39A Gorky str., Chita, 672000



N. S. Soktoeva
Chita State Medical Academy
Russian Federation

39A Gorky str., Chita, 672000



E. P. Bataeva
Chita State Medical Academy
Russian Federation

39A Gorky str., Chita, 672000



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Review

For citations:


Ignatyeva A.V., Kocherova V.V., Soktoeva N.S., Bataeva E.P. Impact of a novel coronavirus infection experienced during pregnancy on perinatal outcomes. Transbaikalian Medical Bulletin. 2023;(3):118-125. (In Russ.) https://doi.org/10.52485/19986173_2023_3_118

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ISSN 1998-6173 (Online)