Modern clinical and pathogenetic aspects, diagnosis and treatment of cerebral palsy
https://doi.org/10.52485/19986173_2023_3_68
Abstract
The leading position in the structure of childhood disability is occupied by cerebral palsy (CP) – a complex and multifaceted disease of the nervous system, affecting various spheres of patients' life. The publication considers the modern understanding of cerebral palsy in children. Epidemiology issues are described, examples of national databases of cerebral palsy patients are given. The causes, pathophysiological mechanisms of cerebral palsy development are characterized. Parallels are drawn between anamnestic, genetic factors and clinical forms of cerebral palsy. Attention is paid to predicting the development of cerebral palsy depending on the concentration of various metabolites in the body. Most of the known biologically active substances lack specificity and are not used in routine clinical practice for the diagnosis of cerebral palsy. Criteria for early diagnosis of cerebral palsy are presented in the publication in terms of age, assessment of movements, and functional activity. The problem of timely diagnosis, formulation depending on etiology is highlighted. Different classifications taking into account topography, severity of motor disorders are discussed. The article presents the main clinical features of the disease and international approaches to treatment and rehabilitation measures based on the review of scientific literature sources.
About the Authors
I. K. Bogomolova
Chita State Medical Academy
Russian Federation
Russian Federation
39A Gorky str., Chita, 672000
T. N. Shil’nikova
Chita State Medical Academy
Russian Federation
Russian Federation
39A Gorky str., Chita, 672000
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For citations:
Bogomolova I.K., Shil’nikova T.N. Modern clinical and pathogenetic aspects, diagnosis and treatment of cerebral palsy. Transbaikalian Medical Bulletin. 2023;(3):68-79. (In Russ.) https://doi.org/10.52485/19986173_2023_3_68
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