CLINICAL CHARACTERISTICS OF THE NEW CORONAVIRUS INFECTION COVID-19 IN THE REPUBLIC OF SAKHA (YAKUTIA)

The aim of the research: to study the clinical picture and risk factors for the severe course of a new coronavirus infection COVID-19 in the provision of specialized medical care in the Republic of Sakha (Yakutia).

Materials and methods of the study: An analysis was made of 404 case histories of patients with a new coronavirus infection COVID-19 who underwent inpatient treatment from 2020 to 2021. The analyzed persons were divided into 2 groups of patients: 150 patients who were hospitalized from 05/19/2020 to 12/31/2020, and in the second group - 254 patients who were hospitalized from 04/01/2021 to 07/31/2021 gg. Data processing was carried out using statistical criteria using the IBM SPSS Statistics 26.0 software package.

Results. The clinical picture in patients with a new coronavirus infection COVID-19 is characterized by the presence of general weakness (94.3%), cough (82.4%), shortness of breath (73.01%), a feeling of pressure in the chest (50.7%) and anosmia (40.8%) in moderate and severe forms of the disease. It was revealed that the risk factors for a severe course of a new coronavirus infection are advanced age - 55.2% of patients were over 60 years old in 2020-2021. (p<0.001); elevated body mass index (BMI): 90.7% of patients with severe NCVI observed in 2020 were diagnosed with overweight and obesity (p<0.001), in 2021 - 47.6%. (p<0.001); the presence of diseases of the cardiovascular system - 35.3% in 2020 and 61.0% in 2021 (p<0.001). Of the 404 people, 39.1% developed severe NKVI (158 people), with more severe cases in 2021 (107 people). The overall mortality was 14.6%, among those with severe NKVI, 28.7% died.

Conclusion. The most common clinical manifestations of NCVI were hyperthermia, severe asthenia, cough, shortness of breath, heaviness and pain in the chest. Among people with severe COVID-19, elderly people (58.4%) prevailed, as well as patients with diseases of the cardiovascular system (57.2%), diabetes mellitus (48.5%) and oncopathology (31.2% ). In the presence of overweight and obesity, a severe course was observed in 65.1%.

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