CLINICAL FEATURES OF ACUTE VIRAL BRONCHIOLITIS IN CHILDREN WITH PREDICTORS OF SEVERITY
https://doi.org/10.52485/19986173_2022_1_71
Abstract
The aim of the research. To study the clinical features of acute viral bronchiolitis in hospitalized children with predictors of its severe course.
Materials and methods. A retrospective analysis of 124 medical records of children in the first year of life with acute viral bronchiolitis who underwent the stage of inpatient treatment from January 2013 to April 2019 was carried out. The subjects were divided into two groups: the first (n=34) with predictors of the severity of viral bronchiolitis, the second (n=90) without risk factors for the development of a serious illness. The quantitative and qualitative signs in the groups were assessed: the development of severe bronchiolitis, the formation of complications, the presence of respiratory failure and its severity, the need for hospitalization in the intensive care unit and oxygen therapy, laboratory markers of bacterial infection.
Results. It was found that in children with severity predictors, viral bronchiolitis in 67.7% proceeds in a severe form, in 32.3% of cases a mild clinical course of the disease develops. Regardless of the presence of risk factors, the severity of the course of bronchiolitis determines the severity of respiratory failure with the predominant registration of severe forms among children with predictors of severity. Children with risk factors for the development of severe bronchiolitis required frequent hospitalization in the intensive care unit (67.7%), non-invasive oxygen therapy (94.1%), the need for mechanical ventilation in the first 6 hours of hospitalization (20.6%) in case of the development of the disease, regardless of the etiological factor of bronchiolitis.
Conclusion. The analysis confirmed the importance of taking into account predictors of the severity of bronchiolitis among young children in connection with the significant risk of developing its severe course, the high need for hospitalization in the intensive care unit, and the development of respiratory failure requiring oxygen therapy. At the same time, the frequency of the formation of severe bronchiolitis among children who do not have traditional predictors of the severity of the disease makes it possible to justify the search for new, including genetic, markers of varying severity of the course of viral bronchiolitis in children.
About the Authors
L. S. Bochkareva
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky str., Chita, 672000
N. A. Miromanova
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky str., Chita, 672000
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Review
For citations:
Bochkareva L.S., Miromanova N.A. CLINICAL FEATURES OF ACUTE VIRAL BRONCHIOLITIS IN CHILDREN WITH PREDICTORS OF SEVERITY. Transbaikalian Medical Bulletin. 2022;(1):71-80. (In Russ.) https://doi.org/10.52485/19986173_2022_1_71
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