THE ROLE OF MACRO- AND MICROELEMENTS IN UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN

The purpose of the article is to generalize modern ideas about the role of the main collagenforming macro-and microelements, their mutual influence on the process of collagen formation in undifferentiated connective tissue dysplasia in children. Many studies have proven the fundamental role of calcium (Ca) and magnesium (Mg) in the formation of collagen. Calcium is the main structural component of the inorganic substance of the collagen matrix and affects the constancy of other elements such as magnesium, zinc, and copper. The deficiency of the essential elements of collagen formation - zinc and copper - leads to a violation of the formation of structural elements of connective tissue, the formation of congenital malformations and changes in the process of osteogenesis. The article presents the negative impact of iodine and selenium deficiency on the formation of connective tissue dysplasia. The authors note that at this time the problem of disadvantage important collagen-forming elements in undifferentiated connective tissue dysplasia in children.

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