SOME CLINICAL AND BIOCHEMICAL PATTERNS IN CHILDREN WITH RICKETS
https://doi.org/10.52485/19986173_2021_3_8
Abstract
Summary. Rickets is a lesion of various organs and systems. The consequences of rickets can be violations of the functioning of the bone system, an imbalance in the cardiovascular system, the gastrointestinal tract, and the immune system. The aim of the study was to identify clinical features and metabolic changes of the bone tissue in rickets in children.
Materials and methods. Biochemical blood samples of 82 patients with rickets and 26 samples of healthy patients were studied. The age of the examined children is from 3 months to 2 years inclusive.
Results. It was found that children have equally frequent acute (46%) and subacute rickets (54%). Based on the study, it was noted that the pathognomonic for the development of rickets is a decrease in the content of calcitriol and calcitonin in the blood serum, an increase in the level of osteoprotegerin, parathyroid hormone and osteocalcin. Characteristic indicators for the acute course are changes in parathyroid hormone and calcitonin, for the subacute course, changes in osteoprotegerin and osteocalcin are characteristic.
About the Authors
I. G. Kargina
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky str., Chita,672000
V. A. Shcherbak
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky str., Chita,672000
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Review
For citations:
Kargina I.G., Shcherbak V.A. SOME CLINICAL AND BIOCHEMICAL PATTERNS IN CHILDREN WITH RICKETS. Transbaikalian Medical Bulletin. 2021;(3):8-12. (In Russ.) https://doi.org/10.52485/19986173_2021_3_8
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