DIAGNOSTIC POTENTIAL OF MUSCLE MASS INDICATORS AS MARKERS OF NUTRITIONAL INSUFFICIENCY IN CANCER PATIENTS

The aim of the research. Тo research muscle mass indicators of computed tomography such as skeletal muscle area and index, as diagnostic markers of nutritional deficiency in cancer patients.

Materials and methods. A prospective study was performed on a sample of cancer patients. Group 1 –with nutritional deficiency (n = 105), group 2 – without nutritional deficiency (n = 96). The groups were balanced by location of the primary tumor (p > 0,05), age (p > 0,05), gender (p > 0,05). Research methods: survey using the Nutritional Risk Screening-2002 questionnaire; anthropometry; study of muscle strength using a dynamometer, testing the speed of five consecutive rises from a chair; measurement of muscle mass by defining of skeletal muscle area, skeletal muscle mass index based on the findings to computed tomography using the program the RadiAnt DICOM VIEWER 2023.1; studying functional capabilities by of the “4-meter walk” test. Statistical processing was performed using IBM SPSS Statistics Version 25.0.

Results. All anthropometric indicators, muscle strength, functional capabilities were decreased in cancer patients with nutritional deficiency. Skeletal muscle area and mass index taking into account gender differences were decreased in cancer patients with nutritional deficiency. Skeletal muscle area value was decreased for 45,8% of patients with a negative result of nutritional screening. The functional capabilities in these patients had no different to the values of patients with confirmed nutritional deficiency. The correlations between Skeletal muscle area and markers of nutritional deficiency have been identified.

Conclusion. Given the widespread use of computed tomography, the area of skeletal muscles can be recommended as an additional objective diagnostic criterion for nutritional deficiency.

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