Authenticity interference of heterogeneous perioperative volemic correction for exponents of hemostasis, electrolyte and acid-base

The aim of the research. Finding the design of sporadic connections between the sovereign changing exponents of hemostasis, electrolyte and acid-base blood composition of patients depending on the implementation of heterogeneous perioperative volemic correction to determine its most favorable variation.

Materials and methods. The study had 80 patients divided into two groups. In group I, liquid supply was carried out with a Ringer solution, and in group II with sterofundin. The following was determined: deficiency/excess of bases in extracellular fluid, as well as in venous blood and its pH, content of potassium, sodium, chlorine, calcium ionized and magnesium, activated partial thromboplastin time, international normalized ratio and fibrinogen. Studies were carried out before the start of the fluid supply, as well as 12. 24 and 48 hours after the operation. The statistical study included univariate and multivariate comparison, canonical, cluster analysis, and multivariate scaling.

Results. In patients of groups I and II, internal spatial connections of independent variables (features) with personal differences and features were initially recorded. The distribution of the studied signs in patients of group II, unlike patients of group I, after 12 hours practically did not change, compared to the previous term. Distribution of the test indices in patients of group II after 24 hours, compared to patients of group I, had dynamics of minimization of relationships, which suggested minuscule inspiration of sterofundin on the test parameters. After 48 hours, in patients of group I, unlike patients of group II, the connections suggesting negative interference of the Ringer solution on the test indicators were modified and supplemented.

Conclusion. The use of the Ringer solution reforms the internal bonds of exponents of hemostasis, electrolyte and acid-base composition, which indicates its adverse effect on them. The use of sterofundine does not alter the internal spatial relationships of the studied exponents and does not cause their negative kinetics.

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