NEUTROPENIA IN THE NEONATAL PERIOD: QUESTIONS REMAIN. CLINICAL CASE
https://doi.org/10.52485/19986173_2024_4_161
Abstract
Immunodeficiency in the neonatal period is often recorded. Neutro- and lymphopenia of secondary genesis are detected in various infectious diseases of the ante-, intra- and postnatal period of infection. Primary immunodeficiency occurs due to genetic breakdown of the immune system and is included in the syndrome complexes of hereditary and chromosomal diseases. The clinic of immunodeficiency conditions does not have a specific picture, and is realized as a sluggish infectious disease, often leading to sepsis. Newborn children, especially premature infants, have a functionally immature immune system, do not form an adequate immune response when exposed to pathogens, which leads to rapid generalization of infectious diseases. An infectious process against the background of congenital immunodeficiency can lead to death. A clinical example of the development of a generalized infectious process with secondary immunodeficiency clearly shows the difficulty of curating patients with a fatal outcome.
About the Authors
N. G. Popova
Chita State Medical Academy
Russian Federation
Russian Federation
Popova N.G., Candidate of Medical Sciences, Associate Professor of Pediatric
Author ID РИНЦ: 413350,
Author ID Scopus: 56175513400
39a Gorky St., Chita, Russia, 672000
V. V. Kocherova
Chita State Medical Academy
Russian Federation
Russian Federation
Kocherova V.V., Candidate of Medical Sciences, Associate Professor of Pediatric
Author ID РИНЦ: 636482,
Author ID Scopus: 57200200253
39a Gorky St., Chita, Russia, 672000
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Review
For citations:
Popova N.G., Kocherova V.V. NEUTROPENIA IN THE NEONATAL PERIOD: QUESTIONS REMAIN. CLINICAL CASE. Transbaikalian Medical Bulletin. 2024;(4):161-168. (In Russ.) https://doi.org/10.52485/19986173_2024_4_161
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