CLINICAL AND PATHOGENETIC FEATURES OF MULTIFORM EXUDATIVE
https://doi.org/10.52485/19986173_2022_3_99
Abstract
The review article presents up-to-date information on the clinical and pathogenetic features of multiform exudative erythema based on the analysis of available scientific articles indexed in the RSCI, PubMed and Web of Science databases. Erythema multiforme exudative is an immuno-mediated disease, the pathogenesis of which is based on a type 4 hypersensitivity reaction with the appearance of cytotoxic T- lymphocytes in the epithelium. The main cause of the disease has not been identified, but predisposing factors have been identified, which include infectious and/or drug triggers. This disease is characterized by the appearance of acrally located foci-targets, sometimes accompanied by erosions of the mucous membrane of the oral cavity, genitals and eyes. anamnesis of the disease and the results of an objective clinical examination are sufficient to diagnose multiform exudative erythema.
About the Authors
I. V. Kibalina
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
A. A. Smolnikova
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
U. D. Fedotova
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
I. N. Sormolotova
Chita State Medical Academy
Russian Federation
Russian Federation
39a Gorky Street, Chita, 672000
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Review
For citations:
Kibalina I.V., Smolnikova A.A., Fedotova U.D., Sormolotova I.N. CLINICAL AND PATHOGENETIC FEATURES OF MULTIFORM EXUDATIVE. Transbaikalian Medical Bulletin. 2022;(3):99-104. (In Russ.) https://doi.org/10.52485/19986173_2022_3_99
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