zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2021_3_70zabmedvestnik-90Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSМАРКЕРЫ ЭНДОТЕЛИАЛЬНОЙ ДИСФУНКЦИИ ПРИ ГИПОТИРЕОЗЕ: ОБЗОР ЛИТЕРАТУРЫMARKERS OF ENDOTHELIAL DYSFUNCTION IN HYPOTHYROIDISM: REVIEW OF LITERATUREГриньН. О.Grin'N. O.

672000, г. Чита, ул. Горького, 39А

39A Gorky St, Chita, 672000

СеребряковаО. В.SerebryakovaO. V.

672000, г. Чита, ул. Горького, 39А

39A Gorky St, Chita, 672000  

СеркинД. М.SerkinD. M.

672000, г. Чита, ул. Горького, 39А

39A Gorky St, Chita, 672000  

Федеральное государственное бюджетное образовательное учреждение высшего образования «Читинская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияChita State Medical AcademyRussian Federation202101082024037080Copyright © Гринь Н.О., Серебрякова О.В., Серкин Д.М., 20242024Гринь Н.О., Серебрякова О.В., Серкин Д.М.Grin' N.O., Serebryakova O.V., Serkin D.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/90

В обзоре обобщены данные литературы об эндотелиальной дисфункции при гипотиреозе. Представлены материалы о действии оксида азота на эндотелий сосудов и о способах определения дисфункции эндотелия инвазивным и неинвазивным методами. Обобщены данные о влиянии функции щитовидной железы на эндотелий, в частности рассмотрены вопросы эндотелийзависимой вазодилятации при субклиническом гипотиреозе.

The review summarizes literature data on endothelial dysfunction in hypothyroidism. There are presented materials on action of nitric oxide on vascular endothelium and on methods for determination of endothelial dysfunction by invasive and non-invasive methods. Data on the effect of thyroid function on the endothelium are summarized, in particular, issues of endothelium-dependent vasodilation in subclinical hypothyroidism are considered.

эндотелий сосудовдисфункция эндотелияоксид азотагипотиреозщитовидная железаvessel endotheliumendothelial dysfunctionnitric oxidehypothyroidismthyroid glandИсследование не имело финансовой поддержки.ReferencesВасина Л.В., Петрищев Н.Н., Власов Т.Д. Эндотелиальная дисфункция и ее основные маркеры. Регионарное кровообращение и микроциркуляция. 2017. 16. 1. 4-15.Vasina L.V., Petrishchev N.N., Vlasov T.D. Endothelial dysfunction and its main markers. Regional blood circulation and microcirculation. 2017. 16. 1. 4–15. in Russian.Воробьева Е.Н., Воробьев Р.И., Шарлаева Е.А., Фомичева М.Л., Соколова Г.Г., Казызаева А.С., Батанина И.А. Дисфункция эндотелия при сердечно-сосудистых заболеваниях: факторы риска, методы диагностики и коррекции. Acta Biologica Sibirica. 2016. 2. 1. 21-40. DOI: 10.17116/jnevro201711741107-111.Vorob'eva E.N., Vorob'ev R.I., Sharlaeva E.A., Fomicheva M.L., Sokolova G.G., Kazyzaeva A.S., Batanina I.A. 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The authors declare that there are no conflicts of interest present.