zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2021_2_117zabmedvestnik-76Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSЭНДОСКОПИЧЕСКАЯ ДИАГНОСТИКА ПРЕДРАКОВЫХ ЗАБОЛЕВАНИЙ ПИЩЕВОДАENDOSCOPIC DIAGNOSIS OF PRECANCEROUS ESOPHAGEAL DISEASESСкажутинаТ. В.SkazhutinaT. V.

143400, г. Красногорск, Ильинское шоссе, военный городок «Павшино» 2, корпус В

143400. Krasnogorsk, Ilyinskoye highway,v/g «Pavshino» 2, housing B

ЦепелевВ. Л.TsepelevV. L.

672000, г. Чита, ул. Горького, 39а

672000, Chita, 39A Gorky street

 

Государственное бюджетное учреждение здравоохранения «Красногорская городская больница № 2»РоссияKrasnogorsk City Hospital №2Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Читинская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияChita State Medical AcademyRussian Federation20213107202402117126Copyright © Скажутина Т.В., Цепелев В.Л., 20242024Скажутина Т.В., Цепелев В.Л.Skazhutina T.V., Tsepelev V.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/76

В обзоре обобщены данные литературы о предраковых заболеваниях пищевода, к которым относятся: лейкоплакия, ахалазия кардии, рубцовая стриктура пищевода (постожоговая), папилломатоз на фоне ВПЧ, синдром Пламмера-Винсона, тилоз. Представлены материалы о частоте встречаемости каждой патологии, эндоскопических критериях диагностики. Рассмотрены вопросы дифференциальной диагностики и лечебной тактики при данных заболеваниях.

The review summarizes literature data on precancerous diseases of esophagus such as leukoplakia, achalasia cardia, cicatricial stricture of the esophagus (post-burn), papillomatosis caused by HPV, Plummer-Vinson syndrome, tylosis. The materials presented information about frequency of occurrence of each pathology, diagnostic sighs and criteria. The article describes issues of differential diagnosis and therapeutic tactics in all patology cases.

Пищеводпредраковые заболеваниядиагностикаэндоскопияEsophagusprecancerous diseasesdiagnosticsendoscopyReferencesTorre L.A., Bray F., Siegel R.L., Ferlay J., Lortet-Tieulent J., Jemal A. Global cancer statistics, 2012. CA: a cancer journal for clinicians. 2015. 65. 87-108.Torre L.A., Bray F., Siegel R.L., Ferlay J., Lortet-Tieulent J., Jemal A. Global cancer statistics, 2012. CA: a cancer journal for clinicians. 2015. 65. 87-108.Napier K.J., Scheerer M., Misra S. Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities. World J. Gastrointest. Oncol. May 15, 2014. 6(5). 112-120. doi: 10.4251/wjgo.v6.i5.112.Napier K.J., Scheerer M., Misra S. Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities. World J. Gastrointest. Oncol. May 15, 2014. 6(5). 112-120. doi: 10.4251/wjgo.v6.i5.112.Qie S. et al. Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nature Communications. 2019. DOI: 10.1038/s41467-019-09179-w.Qie S. et al. Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nature Communications. 2019. DOI: 10.1038/s41467-019-09179-w.Трякин А.А., Бесова Н.С., Волков Н.М., Гамаюнов С.В., Гладков О.А., Давыдов М.М. и соавт. Практические рекомендации по лекарственному лечению рака пищевода и пищеводно-желудочного перехода. Злокачественные опухоли: Практические рекомендации RUSSCO #3s2. 2019. 9. 294-307.Tryakin A.A., Besova N.S., Volkov N.M., Gamayunov S.V., Gladkov O.A., Davydov M.M., et.al. Practical guidelines for drug treatment of cancer of esophagus andesophageal-gastric junction. Malignant tumors: Practical guidelines. RUSSCO #3s2. 2019. 9. 294-307. in Russian.American Cancer Society: Cancer Facts and Figures 2020. Atlanta, Ga: American Cancer Society, 2020. Available online. Last accessed May 12, 2020.American Cancer Society: Cancer Facts and Figures 2020. Atlanta, Ga: American Cancer Society, 2020. Available online. Last accessed May 12, 2020.Di. L., Fu. K., Wu. X. et al. Endoscopic features and associated histology of an basaloid squamous cell carcinoma of the esophagus at the very early stage. BMC Cancer 19. 2019. 513. https://doi.org/10.1186/s12885-019-5749-3.Di. L., Fu. K., Wu. X. et al. Endoscopic features and associated histology of an basaloid squamous cell carcinoma of the esophagus at the very early stage. BMC Cancer 19. 2019. 513. https://doi.org/10.1186/s12885-019-5749-3.Sun Y., Zhang T., Wu W., Zhao D., Zhang N., Cui Y., Liu Y., Gu J., Lu P., Xue F., Yu J., Wang J. Risk Factors Associated with Precancerous Lesions of Esophageal Squamous Cell Carcinoma: a Screening Study in a High Risk Chinese Population. J. Cancer. 2019. 10(14). 3284-3290. doi:10.7150/jca.29979.Sun Y., Zhang T., Wu W., Zhao D., Zhang N., Cui Y., Liu Y., Gu J., Lu P., Xue F., Yu J., Wang J. Risk Factors Associated with Precancerous Lesions of Esophageal Squamous Cell Carcinoma: a Screening Study in a High Risk Chinese Population. J. Cancer. 2019. 10(14). 3284-3290. doi:10.7150/jca.29979.Waintraub D.J., Serouya S., Wang L.S. An Incidental Finding of Esophageal Parakeratosis. Clinical Gastroenterology and Hepatology 2016. 14:xxiii.Waintraub D.J., Serouya S., Wang L.S. An Incidental Finding of Esophageal Parakeratosis. Clinical Gastroenterology and Hepatology 2016. 14:xxiii.Huang J. et al. Esophageal Epidermoid Metaplasia in an Obese Patient with Ehlers-Danlos Disease. EC Gastroenterology and Digestive System. 2019. 6 (12). 1-3.Huang J. et al. Esophageal Epidermoid Metaplasia in an Obese Patient with Ehlers-Danlos Disease. EC Gastroenterology and Digestive System. 2019. 6 (12). 1-3.Singhi A., Arnold C., Lam-Himlin D. et al. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod. Pathol. 2017. 30. 1613-1621. https://doi.org/10.1038/modpathol.2017.73.Singhi A., Arnold C., Lam-Himlin D. et al. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod. Pathol. 2017. 30. 1613-1621. https://doi.org/10.1038/modpathol.2017.73.Hernandez P.V., Snyder D., Kahn A., Wang K.K., Katzka D.A., Horsley-Silva J.L. Esophageal Leukoplakia. ACG Case Reports Journal. September 2019. 6(9). e00213. doi: 10.14309/crj.0000000000000213.Hernandez P.V., Snyder D., Kahn A., Wang K.K., Katzka D.A., Horsley-Silva J.L. Esophageal Leukoplakia. ACG Case Reports Journal. September 2019. 6(9). e00213. doi: 10.14309/crj.0000000000000213.Cottreau J., Gruchy S., Kamionek M., Lauwers G.Y., Arnason T. Prevalence of oesophageal epidermoid metaplasia in 1048 consecutive patients and 58 patients with squamous neoplasms. Histopathology. June 2016. 68(7). 988-995. https://doi.org/10.1111/his.12886.Cottreau J., Gruchy S., Kamionek M., Lauwers G.Y., Arnason T. Prevalence of oesophageal epidermoid metaplasia in 1048 consecutive patients and 58 patients with squamous neoplasms. Histopathology. June 2016. 68(7). 988-995. https://doi.org/10.1111/his.12886.Aiolfi A., Asti E., Bonitta G., Bonavinal L. Esophagectomy for endstage achalasia: systematic review and meta-analysis. World J. Surg. 2018. 42. 1469-1476.Aiolfi A., Asti E., Bonitta G., Bonavinal L. Esophagectomy for endstage achalasia: systematic review and meta-analysis. World J. Surg. 2018. 42. 1469-1476.Moonen A., Boeckxstaens G. Current diagnosis and management of achalasia. J. Clin. Gastroenterol. 2014. 48. 484-490.Moonen A., Boeckxstaens G. Current diagnosis and management of achalasia. J. Clin. Gastroenterol. 2014. 48. 484-490.Roman S., Huot L., Zerbib F. et al. High-resolution manometry improves the diagnosis of esophageal motility disorders in patients with dysphagia: a randomized multicenter study. Am. J. Gastroenterol. 2016. 111. 372-380.Roman S., Huot L., Zerbib F. et al. High-resolution manometry improves the diagnosis of esophageal motility disorders in patients with dysphagia: a randomized multicenter study. Am. J. Gastroenterol. 2016. 111. 372-380.Kahrilas P.J., Bredenoord A.J., Fox M. et al. The Chicago classification of esophageal motility disorders, v3.0. Neurogastroenterol. Motil. 2015. 27. 160-174.Kahrilas P.J., Bredenoord A.J., Fox M. et al. The Chicago classification of esophageal motility disorders, v3.0. Neurogastroenterol. Motil. 2015. 27. 160-174.Zaninotto G., Leusink A., Markar S.R. Management of Achalasia in 2019. Curr. Opin. Gastroenterol. 2019 Apr 24. doi: 10.1097/MOG.0000000000000544.Zaninotto G., Leusink A., Markar S.R. Management of Achalasia in 2019. Curr. Opin. Gastroenterol. 2019 Apr 24. doi: 10.1097/MOG.0000000000000544.Cappell M.S., Stavropoulos S.N., Friedel D. Updated Systematic Review of Achalasia, with a Focus on POEM Therapy. Dig. Dis. Sci. 2020 Jan. 65(1). 38-65. doi: 10.1007/s10620-019-05784-3.Cappell M.S., Stavropoulos S.N., Friedel D. Updated Systematic Review of Achalasia, with a Focus on POEM Therapy. Dig. Dis. Sci. 2020 Jan. 65(1). 38-65. doi: 10.1007/s10620-019-05784-3.Le Naoures P., Hamy A., Lerolle N., Métivier E., Lermite E., Venara A. Risk factors for symptomatic esophageal stricture after caustic ingestion-a retrospective cohort study. Dis. Esophagus. 2017 Jun 01. 30(6). 1-6.Le Naoures P., Hamy A., Lerolle N., Métivier E., Lermite E., Venara A. Risk factors for symptomatic esophageal stricture after caustic ingestion-a retrospective cohort study. Dis. Esophagus. 2017 Jun 01. 30(6). 1-6.Скажутина Т.В., Цепелев В.Л. Результаты лечения пациентов с доброкачественными рубцовыми сужениями пищевода методом бужирования. Современные проблемы науки и образования (электронный научный журнал). 2016. 2. 68-74.Skazhutina T.V., Tsepelev V.L. The results of treatment by bougienage method of patients with benigh cicatricial esophageal structures. Modern problems of science and education (electronic scientific journal). 2016. 2. 68-74. in Russian.Cheng Y.F., Chen H.S., Wu S.C., Chen H.C., Hung W.H., Lin C.H., Wang B.Y. Esophageal squamous cell carcinoma and prognosis in Taiwan. Cancer Med. 2018 Sep. 7(9). 4193-4201.Cheng Y.F., Chen H.S., Wu S.C., Chen H.C., Hung W.H., Lin C.H., Wang B.Y. Esophageal squamous cell carcinoma and prognosis in Taiwan. Cancer Med. 2018 Sep. 7(9). 4193-4201.Скажутина Т.В., Цепелев В.Л., Степанов А.В. Внутрипросветные дилатирующие методы лечения доброкачественных рубцовых стриктур пищевода. Современные проблемы науки и образования (электронный научный журнал). 2015. 5. 277-282.Skazhutina T.V., Tsepelev V.L., Stepanov A.V. Intraluminal dilated methods for treatment of benign cicatricial strictures of the esophagus. Modern problems of science and education (electronic scientific journal). 2015. 5. 277-282. in Russian.Скажутина Т.В., Цепелев В.Л. Результаты лечения пациентов с доброкачественными рубцовыми сужениями пищевода эндоскопическим методом. Врач-аспирант. 2016. 76 (3). 15-21.Skazhutina T.V., Tsepelev V.L. The results of endoscopic treatment of patients with benigh cicatricial esophageal structures. Vrach-aspirant. 2016. 76 (3). 15-21. in Russian.Скажутина Т.В., Цепелев В.Л., Степанов А.В. Эндоскопическое лечение рубцовых стриктур пищевода с использованием ионизированной аргоновой плазмы (с комментарием). Хирургия. Журнал им. Н.И. Пирогова. 2016. 10. 16-20.Skazhutina T.V., Tsepelev V.L., Stepanov A.V. Endoscopic treatment of esophageal cicatricial structures using ionized argon plasma (with commentary). Pirogov Russian Journal of Surgery. 2016. 10. 16-20. in Russian.Cho J.Y., Cheung D.Y., Kim T.J., Kim J.K. A Case of Esophageal Squamous Cell Carcinoma in situ Arising from Esophageal Squamous Papilloma. Clin. Endosc. 2019 Jan. 52(1). 72-75. Published on line 2018 Jul 18. doi: 10.5946/ce.2018.058.Cho J.Y., Cheung D.Y., Kim T.J., Kim J.K. A Case of Esophageal Squamous Cell Carcinoma in situ Arising from Esophageal Squamous Papilloma. Clin. Endosc. 2019 Jan. 52(1). 72-75. Published on line 2018 Jul 18. doi: 10.5946/ce.2018.058.d’Huart M.C., Chevaux J.B., Bressenot A.M. et al. Prevalence of esophageal squamous papilloma (ESP) and associated cancer in northeastern France. Endosc. Int. Open. 2015. 3. 101-106.d’Huart M.C., Chevaux J.B., Bressenot A.M. et al. Prevalence of esophageal squamous papilloma (ESP) and associated cancer in northeastern France. Endosc. Int. Open. 2015. 3. 101-106.Pantham G., Ganesan S., Einstadter D., Jin G., Weinberg A., Fass R. Assessment of the incidence of squamous cell papilloma of the esophagus and the presence of high-risk human papilloma virus. Dis. Esophagus. 2017. 30. 1-5.Pantham G., Ganesan S., Einstadter D., Jin G., Weinberg A., Fass R. Assessment of the incidence of squamous cell papilloma of the esophagus and the presence of high-risk human papilloma virus. Dis. Esophagus. 2017. 30. 1-5.Del Genio G., Del Genio F., Schettino P. et al. Esophageal papilloma: flexible endoscopic ablation by radiofrequency. World J. Gastrointest. Endosc. 2015. 7. 290-294.Del Genio G., Del Genio F., Schettino P. et al. Esophageal papilloma: flexible endoscopic ablation by radiofrequency. World J. Gastrointest. Endosc. 2015. 7. 290-294.Field Z., Russin M., Kropf J., Olivier M., Ge L., Galili Y., Carlan S.J.. Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman. Am. J. Case Rep. 2019. 20. 1264-1267. Publishedonline 2019 Aug 27. doi: 10.12659/AJCR.916823.Field Z., Russin M., Kropf J., Olivier M., Ge L., Galili Y., Carlan S.J.. Plummer-Vinson Syndrome and Heart Failure: An Unusual Association in an African American Woman. Am. J. Case Rep. 2019. 20. 1264-1267. Publishedonline 2019 Aug 27. doi: 10.12659/AJCR.916823.Lo K.B., Albano J., Sandhu N., Candelario N. Plummer-Vinson syndrome: improving outcomes with a multidisciplinary approach. Journal of Multidisciplinary Health care. 19 June 2019. 12. 471-477. doi https://doi.org/10.2147/JMDH.S180410.Lo K.B., Albano J., Sandhu N., Candelario N. Plummer-Vinson syndrome: improving outcomes with a multidisciplinary approach. Journal of Multidisciplinary Health care. 19 June 2019. 12. 471-477. doi https://doi.org/10.2147/JMDH.S180410.Hirose T., Funasaka K., Furukawa K., Yamamura T., Ishikawa T., Ohno E., Nakamura M., Kawashima H., Miyahara R., Hirooka Y. Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained. Intern Med. 2019 Mar 15. 58(6). 785-789. Published on line 2018 Nov 19. doi: 10.2169/internalmedicine.1628-18.Hirose T., Funasaka K., Furukawa K., Yamamura T., Ishikawa T., Ohno E., Nakamura M., Kawashima H., Miyahara R., Hirooka Y. Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained. Intern Med. 2019 Mar 15. 58(6). 785-789. Published on line 2018 Nov 19. doi: 10.2169/internalmedicine.1628-18.Goel A., Bakshi S.S., Soni N., Chhavi N. Iron deficiency anemia and Plummer-Vinson syndrome: Current insights. J. Blood Med. 2017. 8. 175-84.Goel A., Bakshi S.S., Soni N., Chhavi N. Iron deficiency anemia and Plummer-Vinson syndrome: Current insights. J. Blood Med. 2017. 8. 175-84.Goel A., Lakshmi C.P., Bakshi S.S., Soni N., Koshy S. Single-center prospective study of Plummer-Vinson syndrome. Dis. Esophagus. 2016 Oct. 29(7). 837-841.Goel A., Lakshmi C.P., Bakshi S.S., Soni N., Koshy S. Single-center prospective study of Plummer-Vinson syndrome. Dis. Esophagus. 2016 Oct. 29(7). 837-841.Surapanenia B.K., Kancharlab P., Vinayekc R., Dutta S.K., Goldfingerb M. Uncommon Endoscopic Findings in a Tylosis Patient: A Case Report. Case Rep. Oncol. 2019. 12. 385-390. DOI: 10.1159/000500082 Published online: May 23, 2019.Surapanenia B.K., Kancharlab P., Vinayekc R., Dutta S.K., Goldfingerb M. Uncommon Endoscopic Findings in a Tylosis Patient: A Case Report. Case Rep. Oncol. 2019. 12. 385-390. DOI: 10.1159/000500082 Published online: May 23, 2019.Ellis A., Risk J.M., Maruthappu T., Kelsell D.P. Tylosis with oesophageal cancer: Diagnosis, management and molecular mechanisms. Orphanet J. Rare Dis. 2015 Sep. 10(1). 126.Ellis A., Risk J.M., Maruthappu T., Kelsell D.P. Tylosis with oesophageal cancer: Diagnosis, management and molecular mechanisms. Orphanet J. Rare Dis. 2015 Sep. 10(1). 126.Cancer Genome Atlas Research Network; Analysis Working Group: Asan University; BC Cancer Agency, et al. Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan. 12. 541(7636):169-75.Cancer Genome Atlas Research Network; Analysis Working Group: Asan University; BC Cancer Agency, et al. Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan. 12. 541(7636):169-75.

The authors declare that there are no conflicts of interest present.