zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2026_1_130zabmedvestnik-506Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSСовременные аспекты диагностики и лечения хронического гастрита, ассоциированного с Helicobacter PyloriCurrent aspects of the diagnosis and treatment of chronic gastritis associated with Helicobacter Pylorihttps://orcid.org/0009-0001-6431-4645КойданП. В.KoydanP. V.

Полина Валерьевна Койдан, ординатор

кафедра педиатрии

672000; ул. Горького, 39а; Чита

resident

Department of Pediatrics

672000; 39a Gorky St.; Chita

polina198809@mail.ruhttps://orcid.org/0000-0002-2032-7612ЩербакВ. А.ShcherbakV. A.

Владимир Александрович Щербак, д. м. н., профессор, заведующий кафедрой

факультет дополнительного профессионального образования; кафедра педиатрии

672000; ул. Горького, 39а; Чита

Author ID РИНЦ 497238, Author ID Scopus 56175430800, Researcher ID WoS K-4626-2017

Doctor of Medical Sciences, Professor, Head of Department

Postgraduate training; Pediatric Department

672000; 39a Gorky St.; Chita

Author ID RSCI 497238, Author ID Scopus 56175430800, Researcher ID WoS K-4626-2017

shcherbak2001@mail.ruФГБОУ ВО «Читинская государственная медицинская академия» Министерства здравоохранения РФРоссияChita State Medical AcademyRussian Federation20261905202601130139Copyright © Койдан П.В., Щербак В.А., 20262026Койдан П.В., Щербак В.А.Koydan P.V., Shcherbak V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/506

   В обзоре обсуждается роль коинфицирования в развитии хронического гастрита, ассоциированного с Helicobacter Pylori. Сочетание с вирусами Эпштейна–Барра, простого герпеса 2 и 6 типов, а также с описторхозом утяжеляет течение гастрита и снижает эффективность эрадикации. Большие надежды возлагаются на искусственный интеллект, способный в режиме реального времени производить сравнение эндоскопической картины желудка с фотографиями, на которых изображены разнообразные варианты патологического процесса, и выдавать заключение с 82 % точностью. В соответствии с консенсусом Маастрихт VI рекомендованы для эрадикации 4 линий, из которых 3-я и 4-я линия относятся к терапии «спасения». Использование растительной пищи, содержащей терпеноиды, полифенолы и алкалоиды, а также применение пробиотиков в сочетании с антибиотиками увеличивают эффективность эрадикации. Перспективным является создание вакцин против Helicobacter Pylori.

   This review discusses the role of coinfection in the development of chronic gastritis associated with Helicobacter pylori. Coinfection with Epstein-Barr virus, herpes simplex virus types 2 and 6, and opisthorchiasis aggravates the course of gastritis and reduces the effectiveness of eradication. High hopes are placed on artificial intelligence, which can compare endoscopic images of the stomach with photographs depicting various pathological processes in real time and provide a diagnosis with 82 % accuracy. According to the Maastricht VI consensus, four lines of eradication are recommended, of which the third and fourth lines are considered salvage therapy. The use of plant foods containing terpenoids, polyphenols, and alkaloids, as well as the use of probiotics in combination with antibiotics, increases the effectiveness of eradication. The development of vaccines against Helicobacter pylori holds promise

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The authors declare that there are no conflicts of interest present.