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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zabmedvestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Забайкальский медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Transbaikalian Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">1998-6173</issn><publisher><publisher-name>Читинская государственная медицинская академия</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52485/19986173_2025_3_129</article-id><article-id custom-type="elpub" pub-id-type="custom">zabmedvestnik-431</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>ФАКТОРЫ РИСКА ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title>RISK FACTORS FOR CORONARY HEART DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7353-7154</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарганеева</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Garganeeva</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гарганеева Наталья Петровна, д.м.н., профессор кафедры общей врачебной практики и поликлинической терапии</p><p>634050, г. Томск, ул. Московский тракт, 2</p></bio><bio xml:lang="en"><p>Garganeeva N.P., Doctor of Medical Sciences, Professor of Department of General Medical Practice and Outpatient Therapy</p><p>2 Moskovsky Trakt St., Tomsk, 634050</p></bio><email xlink:type="simple">garganeeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8493-0058</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрова Марина Михайловна, д.м.н., профессор, заведующий кафедрой поликлинической терапии и семейной медицины с курсом ПО</p><p>660022, г. Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Petrova M.M., Doctor of Medical Sciences, Professor, Head of the Department of Outpatient Therapy and Family Medicine with a course of Postgraduate Education</p><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">stk99@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0091-5265</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шимохина</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shimokhina</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шимохина Наталья Юрьевна, д.м.н., профессор кафедры поликлинической терапии и семейной медицины с курсом ПО</p><p>660022, г. Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Shimokhina N.YU., Doctor of Medical Sciences, Professor of the Department of Outpatient Therapy and Family Medicine with a course of Postgraduate Education</p><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">doctorkardiolog99@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-2510-5326</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарбеева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarbeeva</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарбеева Алина Сергеевна, студент лечебного факультета</p><p>660022, г. Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Tarbeeva A.S., student of the Faculty of Medicine</p><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">tarbeevaalin@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-8115-411X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Позднякова</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pozdnyakova</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Позднякова Дарья Макаровна, студент лечебного факультета</p><p>660022, г. Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Pozdnyakova D.M., student of the Faculty of Medicine</p><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">dashkacucu@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-7813-135X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фукс</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Fuks</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фукс Валерия Евгеньевна, ординатор кафедры поликлинической терапии и семейной медицины с курсом ПО</p><p>660022, г. Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Fuks V.E., resident of the Department of Outpatient Therapy and Family Medicine with a course of Postgraduate Education</p><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">dollore21@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Сибирский государственный медицинский университет» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>студент лечебного факультета, ФГБОУ ВО "Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого" Министерства здравоохранения Российской Федерации, Россия, г. Красноярск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>02</day><month>11</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>129</fpage><lpage>142</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гарганеева Н.П., Петрова М.М., Шимохина Н.Ю., Тарбеева А.С., Позднякова Д.М., Фукс В.Е., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гарганеева Н.П., Петрова М.М., Шимохина Н.Ю., Тарбеева А.С., Позднякова Д.М., Фукс В.Е.</copyright-holder><copyright-holder xml:lang="en">Garganeeva N.P., Petrova M.M., Shimokhina N.Y., Tarbeeva A.S., Pozdnyakova D.M., Fuks V.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zabmedvestnik.ru/jour/article/view/431">https://www.zabmedvestnik.ru/jour/article/view/431</self-uri><abstract><p>Ишемическая болезнь сердца (ИБС) остается одной из ведущих причин смертности и инвалидизации во всем мире, что делает её актуальной темой для изучения и обсуждения. Современный взгляд на проблему ИБС предполагает комплексный подход к пониманию факторов риска, которые способствуют развитию этого заболевания. Традиционно к основным факторам риска относились: гипертония, дислипидемия, курение, сахарный диабет и ожирение. Однако последние исследования показывают, что к этому списку следует добавить и другие аспекты: – генетическую предрасположенность и уровень стресса.Анализ исследований, приводящихся в настоящем обзоре, показывает, что дислипопротеинемия (апоB/апоA1), курение, психосоциальные факторы, сахарный диабет, артериальная гипертензия, абдоминальное ожирение, алкоголь, низкая физическая активность, недостаточное потребление фруктов являются наиболее значимыми факторами риска развития ишемической болезни сердца. В последнее время особое внимание обращается на психоэмоциональные/психосоциальные факторы, требующие тщательной проработки в рамках профилактики, лечения и реабилитации пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Coronary heart disease (CHD) remains one of the leading causes of death and disability worldwide, which makes it an urgent topic for study and discussion. The modern view of the problem of coronary heart disease suggests an integrated approach to understanding the risk factors that contribute to the development of this disease. Traditionally, the main risk factors were hypertension, dyslipidemia, smoking, diabetes mellitus, and obesity. However, recent research shows that other aspects should be added to this list: genetic predisposition and stress levels.An analysis of the studies presented in this review shows that dyslipoproteinemia (ApoV/ApoA1), smoking, psychosocial factors, diabetes mellitus, hypertension, abdominal obesity, alcohol, low physical activity, and insufficient fruit intake are the most significant risk factors for coronary heart disease. Recently, special attention has been paid to psychoemotional/psychosocial factors that require careful consideration in the framework of prevention, treatment and rehabilitation of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>факторы риска</kwd><kwd>инфаркт миокарда</kwd><kwd>артериальная гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Coronary heart disease</kwd><kwd>cardiovascular diseases</kwd><kwd>risk factors</kwd><kwd>myocardial infarction</kwd><kwd>arterial hypertension</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках государственного задания ФГБОУ ВО КрасГМУ им. проф. В. Ф. Войно-Ясенецкого Минздрава России (2023-2025) «Разработка персонализированного алгоритма диагностики сосудистой умеренной когнитивной дисфункции на фоне перенесенного острого инфаркта миокарда на основе новых генетических и биохимических биомаркеров», № 123022800057-6.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Møller A.L., Vasan R.S., Levy D., Andersson Ch., Lin H. Integrated omics analysis of coronary artery calcific ations and myocardial infarction: the Framingham Heart Study. Scientific Reports. 2023 Dec 7. 13(1). 21581. doi: 10.1038/s41598-023-48848-1.</mixed-citation><mixed-citation xml:lang="en">Møller A.L., Vasan R.S., Levy D., Andersson Ch., Lin H. Integrated omics analysis of coronary artery calcific ations and myocardial infarction: the Framingham Heart Study. 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