zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2024_2_90zabmedvestnik-37Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSПАТОГЕНЕЗ, ДИАГНОСТИКА И ЛЕЧЕНИЕ ОСТРОГО ПОЧЕЧНОГО ПОВРЕЖДЕНИЯ У ПАЦИЕНТОВ С КОРОНАВИРУСНОЙ ИНФЕКЦИЕЙ COVID-19PATHOGENESIS, DIAGNOSIS AND TREATMENT OF ACUTE RENAL INJURY IN PATIENTS WITH CORONAVIRUS INFECTION COVID-19ДацА. В.DatsA. V.

664049, г. Иркутск, м/р Юбилейный, 100

4, 100 Yubileyny microdistrict, 664049 Irkutsk

ДацЛ. С.DatsL. S.

664049, г. Иркутск, м/р Юбилейный, 100

4, 100 Yubileyny microdistrict, 664049 Irkutsk

Иркутская государственная медицинская академия последипломного образования – филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РФРоссияIrkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian FederationRussian Federation2024240720240290101Copyright © Дац А.В., Дац Л.С., 20242024Дац А.В., Дац Л.С.Dats A.V., Dats L.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/37

В обзорной статье представлен анализ научных статей, индексируемых в базах данных PubMed и Web of Science, посвященных патофизиологическим и клиническим особенностям острого почечного повреждения у пациентов с новой коронавирусной инфекцией. Наряду с прямым повреждающим воздействием вируса SARS-CoV-2 на почки и системным последствием вирусной инфекции существуют общие повреждающие факторы острого почечного повреждения для всех критических состояний. Данные о прямом повреждающем воздействии вируса и системном последствии вирусной инфекции противоречивы и требуют дальнейших исследований. Гиповолемия часто встречается на ранних стадиях COVID-19, поэтому экстренное введение жидкости имеет решающее значение для профилактики и лечения острого почечного повреждения у пациентов с новой коронавирусной инфекцией. Оптимизация волемического объема с целью профилактики и предотвращения прогрессирования ОПП до тяжелой степени, требующей проведения заместительной почечной терапии, приобретает особую значимость при ограничении ресурсов в условиях пандемии.

The review article presents an analysis of scientific articles indexed in the PubMed and Web of Science databases on the pathophysiological and clinical features of acute renal injury in patients with a new coronavirus infection. In addition to the direct damaging effects of the SARS-CoV-2 virus on the kidneys and the systemic consequence of viral infection, there are common damaging factors of acute renal injury for all critical conditions. Data on the direct damaging effects of the virus and the systemic consequence of viral infection are contradictory and require further research. Hypovolemia is common in the early stages of COVID-19, so emergency fluid administration is critical for the prevention and treatment of acute kidney injury in patients with novel coronavirus infection. Optimization of liquid volume in order to prevent and prevent the progression of AKI to a severe degree requiring renal replacement therapy is of particular importance when resources are limited in a pandemic.

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The authors declare that there are no conflicts of interest present.