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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zabmedvestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Забайкальский медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Transbaikalian Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">1998-6173</issn><publisher><publisher-name>Читинская государственная медицинская академия</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52485/19986173_2025_1_229</article-id><article-id custom-type="elpub" pub-id-type="custom">zabmedvestnik-323</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ, ИЛЛЮСТРИРОВАННЫЕ КЛИНИЧЕСКИМ НАБЛЮДЕНИЕМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS ILLUSTRATED WITH CLINICAL CASE STUDIES</subject></subj-group></article-categories><title-group><article-title>Холангиокарцинома, связанная с беременностью</article-title><trans-title-group xml:lang="en"><trans-title>Cholangiocarcinoma associated with pregnancy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8973-753X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Троицкая</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Troitskaya</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Троицкая Наталья Игоревна - к.м.н., доцент кафедры онкологии.</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Natalya I. Troitskaya - Candidate of Medical Sciences, Associate Professor of the Department of Oncology.</p><p>39a Gorky st., Chita, 672000</p></bio><email xlink:type="simple">troicachita@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8282-3056</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лузина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Luzina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лузина Елена Владимировна - к.м.н., доцент кафедры терапии факультета дополнительного профессионального образования, председатель Забайкальского научного общества гастроэнтерологов.</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Elena V. Luzina - Candidate of Medical Sciences, Associate Professor of the Department of Therapy Faculty of Additional Professional Education; Chairman of the Transbaikal Scientific Society of gastroenterologists.</p><p>39a Gorky st., Chita, 672000</p></bio><email xlink:type="simple">el.luz@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федорова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федорова Лариса Викторовна, заведующая отделением гастроэнтерологии.</p><p>672038, Чита, ул. Коханского, д. 7</p></bio><bio xml:lang="en"><p>Larisa V. Fedorova - Head of the Gastroenterology Department.</p><p>7 Kokhansky St., Chita, 672038</p></bio><email xlink:type="simple">sirens_07@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Читинская государственная медицинская академия» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГУЗ «Краевая клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>08</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>229</fpage><lpage>236</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Троицкая Н.И., Лузина Е.В., Федорова Л.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Троицкая Н.И., Лузина Е.В., Федорова Л.В.</copyright-holder><copyright-holder xml:lang="en">Troitskaya N.I., Luzina E.V., Fedorova L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zabmedvestnik.ru/jour/article/view/323">https://www.zabmedvestnik.ru/jour/article/view/323</self-uri><abstract><p>Холангиокарцинома — это редкое и агрессивное злокачественное новообразование с продолжительностью жизни в среднем 3–6 месяцев после диагностики. Частота заболевания составляет 0,58 на 100 тысяч населения. Ранние симптомы, такие как дискомфорт и снижение аппетита, неспецифичны, в то время как поздние стадии характеризуются механической желтухой в 90% случаев. В статье рассмотрен случай выявления холангиокарциномы у 37-летней пациентки, диагностированный в послеродовом периоде. Обсуждение случая подчеркивает сложности диагностики данного злокачественного новообразования, особенно во время беременности. Низкая частота заболевания и разнообразие причин механической желтухи затрудняют раннюю диагностику, что часто приводит к выявлению заболевания на терминальных стадиях. Для улучшения исходов необходимо повышенное внимание со стороны врачей к онкологическим заболеваниям у беременных.</p></abstract><trans-abstract xml:lang="en"><p>Cholangiocarcinoma is a rare and aggressive malignant neoplasm with an average life expectancy of 3–6 months after diagnosis. The incidence of the disease is 0,58 per 100,000 population. Early symptoms, such as discomfort and decreased appetite, are nonspecific, while late stages are characterized by mechanical jaundice in 90% of cases. This article discusses a case of cholangiocarcinoma diagnosed in a 37-year-old patient during the postpartum period. The discussion emphasizes the difficulties in diagnosing this malignant neoplasm, especially during pregnancy. The low incidence of the disease and the variety of causes of mechanical jaundice complicate early diagnosis, often leading to the identification of the disease at terminal stages. To improve outcomes, increased attention from healthcare professionals to oncological diseases in pregnant women is necessary.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>холангиокарцинома</kwd><kwd>беременность</kwd><kwd>механическая желтуха</kwd><kwd>злокачественное новообразование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cholangiocarcinoma</kwd><kwd>pregnancy</kwd><kwd>mechanical jaundice</kwd><kwd>malignant neoplasm</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Замотина А.Г., Фалалеева Н.А., Кучеров В.В. и соавт. Холангиокарцинома. Эпидемиология, классификация, диагностика, методы лечения (обзор литературы). Клинический разбор в общей медицине. 2024. 5 (7). 12–16.</mixed-citation><mixed-citation xml:lang="en">Zamotina A. G., Falaleeva N. A., Kucherov V. V. et al. Cholangiocarcinoma. 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