<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zabmedvestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Забайкальский медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Transbaikalian Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">1998-6173</issn><publisher><publisher-name>Читинская государственная медицинская академия</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52485/19986173_2025_1_121</article-id><article-id custom-type="elpub" pub-id-type="custom">zabmedvestnik-295</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>Интенсивная терапия при тяжёлой ожоговой травме в детском и подростковом возрасте в условиях стационара</article-title><trans-title-group xml:lang="en"><trans-title>Intensive care of children and adolescents with severe burns in hospital settings</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4705-3823</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быков</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykov</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Быков Юрий Витальевич - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310</p></bio><bio xml:lang="en"><p>Yuri V. Bykov - Candidate of Medical Sciences, Assistant of the Department of Anesthesiology and Intensive Care with a course of additional professional education.</p><p>310 Mira st., Stavropol, 355017</p></bio><email xlink:type="simple">yubykov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9990-7272</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Обедин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Obedin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Обедин Александр Николаевич - д.м.н., заведующий кафедрой анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310; 355002, Ставрополь, ул. Семашко, 3/1</p></bio><bio xml:lang="en"><p>Alexander N. Obedin - Doctor of Medical Sciences, Head of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017; 3/1 Semashko st., Stavropol, 355002</p></bio><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4729-5101</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зинченко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinchenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зинченко Олег Васильевич - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310</p></bio><bio xml:lang="en"><p>Oleg V. Zinchenko - Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017</p></bio><email xlink:type="simple">regionar2008@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4460-870X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьёва</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyeva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Муравьёва Алла Анатольевна - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310</p></bio><bio xml:lang="en"><p>Alla A. Muravyeva - Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017</p></bio><email xlink:type="simple">muravyeva81@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5482-8581</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яцук</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yatsuk</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яцук Иван Викторович - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310; 355032, Ставрополь, ул. Тухачевского, 17</p></bio><bio xml:lang="en"><p>Ivan V. Yatsuk - Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017; 17 Tukhachevsky st., Stavropol, 355032</p></bio><email xlink:type="simple">yatsukiv@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9841-6930</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Волков Евгений Владимирович - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310; 355002, Ставрополь, ул. Семашко, 1</p></bio><bio xml:lang="en"><p>Evgeny V. Volkov - Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017; 1 Semashko st., Stavropol, 355002</p></bio><email xlink:type="simple">volkov26@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1494-1613</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фишер</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fischer</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фишер Василий Владимирович - к.м.н., доцент кафедры анестезиологии, реаниматологии с курсом ДПО.</p><p>355017, Ставрополь, ул. Мира, 310; 356240, Ставрополь, ул. Ленина, 1</p></bio><bio xml:lang="en"><p>Vasily V. Fischer - Candidate of Medical Sciences, Associate Professor of the Department of Anesthesiology and Intensive Care with the course of additional professional education.</p><p>310 Mira st., Stavropol, 355017; 1 Lenin st., Stavropol, 356240</p></bio><email xlink:type="simple">vvfisher26@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Министерства здравоохранения РФ; ГБУЗ «Ставропольский краевой клинический перинатальный центр № 1» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University; Stavropol Regional Clinical Perinatal Center No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Министерства здравоохранения РФ; ГБУЗ «Городская клиническая больница скорой медицинской помощи города Ставрополя» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University; Stavropol City Clinical Emergency Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Министерства здравоохранения РФ; ГБУЗ «Ставропольская краевая клиническая больница» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University; Stavropol Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ставропольский государственный медицинский университет» Министерства здравоохранения РФ; ГБУЗ «Шпаковская районная больница» Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical University; Shpakovskaya District Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>08</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>121</fpage><lpage>139</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Быков Ю.В., Обедин А.Н., Зинченко О.В., Муравьёва А.А., Яцук И.В., Волков Е.В., Фишер В.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Быков Ю.В., Обедин А.Н., Зинченко О.В., Муравьёва А.А., Яцук И.В., Волков Е.В., Фишер В.В.</copyright-holder><copyright-holder xml:lang="en">Bykov Y.V., Obedin A.N., Zinchenko O.V., Muravyeva A.A., Yatsuk I.V., Volkov E.V., Fischer V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zabmedvestnik.ru/jour/article/view/295">https://www.zabmedvestnik.ru/jour/article/view/295</self-uri><abstract><p>Тяжёлая ожоговая травма (ОТ) – распространённая клиническая ситуация в практике детской интенсивной терапии, требующая оказания неотложной помощи в условиях отделения реанимации и интенсивной терапии. Ожоговый шок у ребёнка может развиться при наличии 10% площади поражения от общей поверхности тела и в первые часы не имеет выраженных гемодинамических и церебральных нарушений. К общим аспектам оказания экстренной помощи относят восстановление проходимости дыхательных путей, обеспечение венозного доступа, которое может быть затруднено из-за наличия ожогов кожи. Проведение инфузионной терапии при тяжёлой ОТ является обязательным компонентом, при этом предпочтение отдаётся сбалансированным кристаллоидным растворам, а назначение коллоидов является дискутабельным вопросом. Энтеральное питание должно проводиться смесями с высоким содержанием белков, углеводов и микроэлементов. Детям с тяжёлой ОТ необходимо проведение адекватного обезболивания и седации, назначение антибактериальной терапии при выявлении источников возможной инфекции. Осуществляется профилактика стрессовых язв. При наличии декомпенсации по дыхательной системе выполняется интубация трахеи с переводом ребёнка на искусственную вентиляцию лёгких; при наличии острого поражения почек – методы заместительной почечной терапии. Описаны клинические особенности и аспекты интенсивной терапии при ингаляционных ожогах, отравлении угарным газом, цианидами и электротравме в детском и подростковом возрасте. Необходимо усовершенствование неотложной помощи при ОТ в стационаре с целью улучшения результатов интенсивной терапии данному контингенту пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Severe burn injury (BI) is a condition frequently seen in pediatric intensive care practice, and its occurrence requires immediate admission of the patient to the intensive care unit. A child with 10% or more of their total body surface area affected may go into a state of burn shock, which does not produce noticeable hemodynamic and cerebral disturbances in the first few hours. Common aspects of emergency care include restoring airway patency and ensuring venous access, a task that may be complicated by skin burns. In severe BI, one obligatory component is fluid management, preferably with balanced crystalloid solutions, while the use of colloids is controversial. Enteral feeding must rely on formulas rich in protein, carbohydrates and micronutrients. Children with severe BI need adequate pain relief and sedation, as well as antibacterial treatment if an infection is found. Preventive steps should be taken against the development of stress ulcers. In the event of respiratory decompensation, the child is intubated and placed on mechanical ventilation; in the event of acute kidney injury, renal replacement therapy is initiated. The article describes specific details and aspects of intensive therapy in children and adolescents with inhalation injuries, carbon monoxide and cyanide poisoning, and electrical injury. The quality of inpatient emergency care in cases of BI should be improved in order to improve intensive treatment outcomes in this category of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тяжёлая ожоговая травма</kwd><kwd>дети и подростки</kwd><kwd>интенсивная терапия</kwd><kwd>инфузионная терапия</kwd><kwd>анальгезия</kwd><kwd>энтеральное питание</kwd></kwd-group><kwd-group xml:lang="en"><kwd>severe burn injury</kwd><kwd>children and adolescents</kwd><kwd>intensive care</kwd><kwd>fluid management</kwd><kwd>pain relief</kwd><kwd>enteral feeding</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nassar J.Y., Al Qurashi A.A., Albalawi I.A. et al. Pediatric Burns: A Systematic Review and Meta-Analysis on Epidemiology, Gender Distribution, Risk Factors, Management, and Outcomes in Emergency Departments. Cureus. 2023. 15 (11). P. 49012. DOI: 10.7759/cureus.49012</mixed-citation><mixed-citation xml:lang="en">Nassar J.Y., Al Qurashi A.A., Albalawi I.A. et al. Pediatric Burns: A Systematic Review and Meta-Analysis on Epidemiology, Gender Distribution, Risk Factors, Management, and Outcomes in Emergency Departments. Cureus. 2023. 15(11). P. 49012. DOI: 10.7759/cureus.49012</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Suman A., Owen J. Update on the management of burns in paediatrics. BJA Educ. 2020. 20 (3). 103–110. DOI: 10.1016/j.bjae.2019.12.002.</mixed-citation><mixed-citation xml:lang="en">Suman A, Owen J. Update on the management of burns in paediatrics. BJA Educ. 2020. 20(3). 103–110. DOI: 10.1016/j.bjae.2019.12.002</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Datta P.K., Chowdhury S.R., Aravindan A. et al. Medical and Surgical Care of Critical Burn Patients: A Comprehensive Review of Current Evidence and Practice. Cureus. 2022. 14 (11). P. e31550. DOI: 10.7759/cureus.31550.</mixed-citation><mixed-citation xml:lang="en">Datta P.K., Chowdhury S.R., Aravindan A. et al. Medical and Surgical Care of Critical Burn Patients: A Comprehensive Review of Current Evidence and Practice. Cureus. 2022. 14(11). P. e31550. DOI: 10.7759/cureus.31550</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Regan A., Hotwagner D.T. Burn Fluid Management. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.</mixed-citation><mixed-citation xml:lang="en">Regan A., Hotwagner D.T. Burn Fluid Management. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y., Deng K., Qian J., et al. Use of extracorporeal membrane oxygenation in children with burn injury: Case report and literature review. Medicine (Baltimore). 2023. 102 (24). P. 34029. DOI: 10.1097/MD.0000000000034029.</mixed-citation><mixed-citation xml:lang="en">Wang Y., Deng K., Qian J., et al.. Use of extracorporeal membrane oxygenation in children with burn injury: Case report and literature review. Medicine (Baltimore). 2023. 102(24). P. 34029. DOI: 10.1097/MD.0000000000034029</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Woolard A., Hill N.T., McQueen M. et al. The psychological impact of paediatric burn injuries: a systematic review. BMC Public Health. 2021. 21. P. 2281. DOI: 10.1186/s12889-021-12296-1</mixed-citation><mixed-citation xml:lang="en">Woolard A., Hill N.T., McQueen M. et al. The psychological impact of paediatric burn injuries: a systematic review. BMC Public Health. 2021. 21. P. 2281. DOI: 10.1186/s12889-021-12296-1</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Arpacık M., Kaymakc A. Knowledge level on the management of pediatric burn patients among physicians working in the emergency department. Ulus Travma Acil Cerrahi Derg. 2023. 29 (1). P. 73–80. DOI: 10.14744/tjtes.2022.85781.</mixed-citation><mixed-citation xml:lang="en">Arpacık M., Kaymakc A. Knowledge level on the management of pediatric burn patients among physicians working in the emergency department. Ulus Travma Acil Cerrahi Derg. 2023. 29(1). P. 73–80. DOI: 10.14744/tjtes.2022.85781</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schaefer T.J., Lopez J.N. Burn Resuscitation and Management. StatPearls [Internet]. 2023.</mixed-citation><mixed-citation xml:lang="en">Schaefer T.J., Lopez J.N. Burn Resuscitation and Management. StatPearls [Internet]. 2023.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chung B.Y., Kim H.B., Jung M.J. et al. Post-burn pruritus. Int J Mol Sci. 2020. 21. DOI: 10.3390/ijms21113880.</mixed-citation><mixed-citation xml:lang="en">Chung B.Y., Kim H.B., Jung M.J. et al. Post-burn pruritus. Int J Mol Sci. 2020. 21. DOI: 10.3390/ijms21113880</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Żwierełło W., Piorun K., Skórka-Majewicz M. et al. Burns: Classification, Pathophysiology, and Treatment: A Review. Int J Mol Sci. 2023. 24 (4). Р. 3749. DOI: 10.3390/ijms24043749.</mixed-citation><mixed-citation xml:lang="en">Żwierełło W., Piorun K., Skórka-Majewicz M. et al. Burns: Classification, Pathophysiology, and Treatment: A Review. Int J Mol Sci. 2023. 24(4). Р. 3749. DOI: 10.3390/ijms24043749</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Азовский Д.К., Лекманов А.У., Пилютик С.Ф., Махмутова Г.Р. Интенсивная терапия ожоговой травмы у детей в острый период: тенденции и проблемы. Медицинский алфавит. 2017. 17. 22–25.</mixed-citation><mixed-citation xml:lang="en">Azovsky D.K., Lekmanov A.U., Pilyutyk S.F., Makhmutova G.R. Intensive care of burn injury in children in the acute period: trends and problems. Medical alphabet. 2017. 17. 22-25.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации. Ожоги термические и химические. Ожоги солнечные. Ожоги дыхательных путей. 2021.</mixed-citation><mixed-citation xml:lang="en">Clinical recommendations. Burns are thermal and chemical. Sunburns. Burns of the respiratory tract. 2021.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">American Burn Association. Chicago: American Burn Association. Advanced burn life support course: provider manual 2018 Update.</mixed-citation><mixed-citation xml:lang="en">American Burn Association. Chicago: American Burn Association. Advanced burn life support course: provider manual 2018 Update.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Strobel A.M., Fey R. Emergency care of pediatric burns. Emerg Med Clin North Am. 2018. 36. 441–58. DOI: 10.1016/j.emc.2017.12.011.</mixed-citation><mixed-citation xml:lang="en">Strobel A.M., Fey R. Emergency care of pediatric burns. Emerg Med Clin North Am. 2018. 36. 441–58. DOI: 10.1016/j.emc.2017.12.011</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Radzikowska-Büchner E., Łopuszyńska I., Flieger W. et al. An Overview of Recent Developments in the Management of Burn Injuries. Int J Mol Sci. 2023. 24 (22). 16357. DOI: 10.3390/ijms242216357.</mixed-citation><mixed-citation xml:lang="en">Radzikowska-Büchner E., Łopuszyńska I., Flieger W. et al. An Overview of Recent Developments in the Management of Burn Injuries. Int J Mol Sci. 2023. 24(22). 16357. DOI: 10.3390/ijms242216357</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Romanowski K.S., Carson J., Pape K. et al. American Burn Association guidelines on the management of acute pain in the adult burn patient: a review of the literature, a compilation of expert opinion, and next steps. J Burn Care Res. 2020. 41. 1129–1151. DOI: 10.1093/jbcr/iraa119.</mixed-citation><mixed-citation xml:lang="en">Romanowski K.S., Carson J., Pape K. et al. American Burn Association guidelines on the management of acute pain in the adult burn patient: a review of the literature, a compilation of expert opinion, and next steps. J Burn Care Res. 2020. 41. 1129–1151. DOI: 10.1093/jbcr/iraa119</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Haberal M., Abali A.U., Karakayali H. Fluid management in major burn injuries. Indian J Plast Surg. 2020. 43. 29–36. DOI: 10.4103/0970-0358.70715.</mixed-citation><mixed-citation xml:lang="en">Haberal M., Abali A.U., Karakayali H. Fluid management in major burn injuries. Indian J Plast Surg. 2020. 43. 29–36. DOI: 10.4103/0970-0358.70715</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Singh S., Kerndt C.C., Davis D. StatPearls. Treasure Island: StatPearls Publishing; 2021.</mixed-citation><mixed-citation xml:lang="en">Singh S., Kerndt C.C., Davis D. StatPearls. Treasure Island: StatPearls Publishing; 2021.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Habib M., Saadah L., Al-Samerrae M. et al. Does Ringer lactate used in Parkland formula for burn resuscitation adequately restore body electrolytes and proteins? // Modern Plastic Surg. 2017. 7. 1–12.</mixed-citation><mixed-citation xml:lang="en">Habib M., Saadah L., Al-Samerrae M. et al. Does Ringer lactate used in Parkland formula for burn resuscitation adequately restore body electrolytes and proteins? // Modern Plastic Surg. 2017. 7. 1–12.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Navickis R.J., Greenhalgh D.G., Wilkes M.M. Albumin in burn shock resuscitation: a meta-analysis of controlled clinical trials. J Burn Care Res. 2016. 37. 268–278. DOI: 10.1097/BCR.0000000000000201.</mixed-citation><mixed-citation xml:lang="en">Navickis R.J., Greenhalgh D.G., Wilkes M.M. Albumin in burn shock resuscitation: a meta-analysis of controlled clinical trials. J Burn Care Res. 2016. 37. 268–278. DOI: 10.1097/BCR.0000000000000201</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Müller Dittrich M.H., de Carvalho W.B., Lavado E.D. Evaluation of the "Early" Use of Albumin in Children with Extensive Burns: A Randomized Controlled Trial. Pediatr Crit. Care Med. 2016. 17. 280-6. DOI: 10.1097/PCC.0000000000000728.</mixed-citation><mixed-citation xml:lang="en">Müller Dittrich M.H., de Carvalho W.B., Lavado E.D. Evaluation of the "Early" Use of Albumin in Children with Extensive Burns: A Randomized Controlled Trial. Pediatr Crit. Care Med. 2016. 17. 280-6. DOI: 10.1097/PCC.0000000000000728</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Clark A., Neyra J.A., Madni T. et al. Acute kidney injury after burn. Burns. 2017. 43. 898–908. DOI: 10.1016/j.burns.2017.01.023.</mixed-citation><mixed-citation xml:lang="en">Clark A., Neyra J.A., Madni T. et al. Acute kidney injury after burn. Burns. 2017. 43. 898–908. DOI: 10.1016/j.burns.2017.01.023</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Kaur S., Auger C., Jeschke M.G. Adipose tissue metabolic function and dysfunction: impact of burn injury. Front Cell Dev Biol. 2020. Vol. 8. 599576. DOI: 10.3389/fcell.2020.599576.</mixed-citation><mixed-citation xml:lang="en">Kaur S., Auger C., Jeschke M.G. Adipose tissue metabolic function and dysfunction: impact of burn injury. Front Cell Dev Biol. 2020. Vol. 8. 599576. DOI: 10.3389/fcell.2020.599576</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Singer P., Blaser A.R., Berger M.M. et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019. 38. 48–79. DOI: 10.1016/j.clnu.2018.08.037.</mixed-citation><mixed-citation xml:lang="en">Singer P., Blaser A.R., Berger M.M. et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019. 38. 48–79. DOI: 10.1016/j.clnu.2018.08.037</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Walsh K., Stiles K., Dheansa B. Concerns relating to the European resuscitation guidelines for the first aid management of burns. Burns. 2016. 42 (1). 240–241. DOI: 10.1016/j.burns.2015.11.005.</mixed-citation><mixed-citation xml:lang="en">Walsh K., Stiles K., Dheansa B. Concerns relating to the European resuscitation guidelines for the first aid management of burns. Burns. 2016. 42(1). 240-241. DOI: 10.1016/j.burns.2015.11.005</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ciornei B., David V.L., Popescu D., et al. Pain Management in Pediatric Burns: A Review of the Science behind It. Glob Health Epidemiol Genom. 2023. 2023. 9950870. DOI: 10.1155/2023/9950870.</mixed-citation><mixed-citation xml:lang="en">Ciornei B., David V.L., Popescu D., et al. Pain Management in Pediatric Burns: A Review of the Science behind It. Glob Health Epidemiol Genom. 2023. 2023. 9950870. DOI: 10.1155/2023/9950870</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Gill P., Falder S. Early management of paediatric burn injuries. Paediatr Child Health. 2017. 27. 406–414.</mixed-citation><mixed-citation xml:lang="en">Gill P., Falder S. Early management of paediatric burn injuries. Paediatr Child Health. 2017. 27. 406–414.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Guarino M., Perna B., Cesaro A.E. et al. 2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department. J Clin Med. 2023. 12. 3188. DOI: 10.3390/jcm12093188.</mixed-citation><mixed-citation xml:lang="en">Guarino M., Perna B., Cesaro A.E. et al. 2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department. J Clin Med. 2023. 12. 3188. DOI: 10.3390/jcm12093188</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">van Duin D., Strassle P.D., DiBiase L.M. et al. Timeline of health care-associated infections and pathogens after burn injuries. Am J Infect Control. 2016. 44. 1511–1516. DOI: 10.1016/j.ajic.2016.07.027.</mixed-citation><mixed-citation xml:lang="en">van Duin D., Strassle P.D., DiBiase L.M. et al. Timeline of health care-associated infections and pathogens after burn injuries. Am J Infect Control. 2016. 44. 1511–1516. DOI: 10.1016/j.ajic.2016.07.027</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Rubio-Regidor M., Martín-Pellicer A., Silvestri L. et al. Digestive decontamination in burn patients: a systematic review of randomized clinical trials and observational studies. Burns. 2018. 44. 16–23. DOI: 10.1016/j.burns.2017.04.001.</mixed-citation><mixed-citation xml:lang="en">Rubio-Regidor M., Martín-Pellicer A., Silvestri L. et al. Digestive decontamination in burn patients: a systematic review of randomized clinical trials and observational studies. Burns. 2018. 44. 16–23. DOI: 10.1016/j.burns.2017.04.001</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Siddiqui A.H., Farooq U., Siddiqui F. StatPearls. Treasure Island: StatPearls Publishing; 2022.</mixed-citation><mixed-citation xml:lang="en">Siddiqui A.H., Farooq U., Siddiqui F. StatPearls. Treasure Island: StatPearls Publishing; 2022.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Walker P.F., Buehner M.F., Wood L.A. et al. Diagnosis and management of inhalation injury: an updated review. Crit Care. 2015. 19. 351. DOI: 10.1186/s13054-015-1077-4.</mixed-citation><mixed-citation xml:lang="en">Walker P.F., Buehner M.F., Wood L.A. et al. Diagnosis and management of inhalation injury: an updated review. Crit Care. 2015. 19. 351. DOI: 10.1186/s13054-015-1077-4</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Duan Z., Cai G., Li J. et al. Meta-analysis of renal replacement therapy for burn patients: incidence rate, mortality, and renal outcome. Front Med (Lausanne). 2021. 8. 708533. DOI: 10.3389/fmed.2021.708533.</mixed-citation><mixed-citation xml:lang="en">Duan Z., Cai G., Li J. et al. Meta-analysis of renal replacement therapy for burn patients: incidence rate, mortality, and renal outcome. Front Med (Lausanne). 2021. 8. 708533. DOI: 10.3389/fmed.2021.708533</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">McGinn K.A., Weigartz K., Lintner A. et al. Nebulized heparin with N-acetylcysteine and albuterol reduces duration of mechanical ventilation in patients with inhalation injury. J Pharm Pract. 2019. 32. 163–166. DOI: 10.1177/0897190017747143.</mixed-citation><mixed-citation xml:lang="en">McGinn K.A., Weigartz K., Lintner A. et al. Nebulized heparin with N-acetylcysteine and albuterol reduces duration of mechanical ventilation in patients with inhalation injury. J Pharm Pract. 2019. 32. 163–166. DOI: 10.1177/0897190017747143</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">David G., Greenhalgh M.D. Management of burns. N Engl J Med. 2019. 380. 2349–2359. DOI: 10.1056/NEJMra1807442.</mixed-citation><mixed-citation xml:lang="en">David G., Greenhalgh M.D. Management of burns. N Engl J Med. 2019. 380. 2349–2359. DOI: 10.1056/NEJMra1807442</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen J.S., Sally M., Mullins R.J. et al. Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited. Am J Surg. 2017. 213. 73–79. DOI: 10.1016/j.amjsurg.2016.03.017.</mixed-citation><mixed-citation xml:lang="en">Nielsen J.S., Sally M., Mullins R.J. et al. Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited. Am J Surg. 2017. 213. 73–79. DOI: 10.1016/j.amjsurg.2016.03.017</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
