zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2023_3_118zabmedvestnik-209Research ArticleНАУЧНЫЕ ОБЗОРЫ, ИЛЛЮСТРИРОВАННЫЕ КЛИНИЧЕСКИМ НАБЛЮДЕНИЕМSCIENTIFIC REVIEWS ILLUSTRATED WITH CLINICAL CASE STUDIESВлияние новой коронавирусной инфекции, перенесенной матерью во время беременности, на перинатальные исходыImpact of a novel coronavirus infection experienced during pregnancy on perinatal outcomesИгнатьеваА. В.IgnatyevaA. V.

672000, г. Чита, ул. Горького, 39 А

39A Gorky str., Chita, 672000

КочероваВ. В.KocherovaV. V.

672000, г. Чита, ул. Горького, 39 А

39A Gorky str., Chita, 672000

СоктоеваН. С.SoktoevaN. S.

672000, г. Чита, ул. Горького, 39 А

39A Gorky str., Chita, 672000

БатаеваЕ. П.BataevaE. P.

672000, г. Чита, ул. Горького, 39 А

39A Gorky str., Chita, 672000

Федеральное государственное бюджетное образовательное учреждение высшего образования «Читинская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияChita State Medical AcademyRussian Federation20230608202403118125Copyright © Игнатьева А.В., Кочерова В.В., Соктоева Н.С., Батаева Е.П., 20242024Игнатьева А.В., Кочерова В.В., Соктоева Н.С., Батаева Е.П.Ignatyeva A.V., Kocherova V.V., Soktoeva N.S., Bataeva E.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/209

С начала пандемии COVID-19 появлялись сообщения об особенностях течения новой коронавирусной инфекции в особой группе пациентов – беременных женщин. Физиологические, иммунологические изменения в организме беременной приводят к преобразованию врожденных и адаптивных иммунных реакций из воспалительного фенотипа в противовоспалительный, подавляя реакции иммунного отторжения плода и способствуя пассивной передаче материнских антител к плоду. В настоящее время имеются данные о возможной вертикальной передачи новой короновирусной инфекции от матери к плоду и воздействии SARS-CoV2 на плод, на тромбогенную направленность гемостаза, с развитием неблагоприятных исходов. Представлен обзор данных литературы, иллюстрированный клиническим случаем неблагоприятного перинатального исхода перенесенной инфекции COVID-19 во время беременности, с развитием нарушения гемостаза у новорожденного.

Since the beginning of the COVID-19 pandemic, there have been reports about the peculiarities of the course of a new coronavirus infection in a special group of patients - pregnant women. Physiological, immunological changes in the pregnant woman's body lead to the transformation of innate and adaptive immune responses from an inflammatory phenotype to an anti-inflammatory one, suppressing fetal immune rejection reactions and contributing to the passive transmission of maternal antibodies to the fetus. Currently, there is evidence of possible vertical transmission of a new coronavirus infection from mother to fetus and the impact of SARS-CoV2 on the fetus on the thrombogenic orientation of its hemostasis, with the development of adverse outcomes. Literature review and clinical case of an unfavorable perinatal outcome of a COVID-19 infection during pregnancy with the development of hemostasis disorder in a newborn are presented.

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The authors declare that there are no conflicts of interest present.