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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zabmedvestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Забайкальский медицинский вестник</journal-title><trans-title-group xml:lang="en"><trans-title>Transbaikalian Medical Bulletin</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">1998-6173</issn><publisher><publisher-name>Читинская государственная медицинская академия</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52485/19986173_2023_2_151</article-id><article-id custom-type="elpub" pub-id-type="custom">zabmedvestnik-179</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>РИАНОДИНОВЫЕ КАНАЛЫ КАЛЬЦИЯ И ИХ РОЛЬ   В СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ</article-title><trans-title-group xml:lang="en"><trans-title>RIANODINE CALCIUM CHANNELS AND THEIR ROLE   IN CARDIOVASCULAR PATHOLOGY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пушкарёв</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pushkarev</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>672000 г.Чита, ул. Горького, 39а </p></bio><bio xml:lang="en"><p>39а Gorky St., Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Большакова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bolshakova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>672000 г.Чита, ул. Горького, 39а </p></bio><bio xml:lang="en"><p>39а Gorky St., Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Покоева</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pokoeva</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>672000 г.Чита, ул. Горького, 39а </p></bio><bio xml:lang="en"><p>39а Gorky St., Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Витковский</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vitkovsky</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>672000 г.Чита, ул. Горького, 39а </p></bio><bio xml:lang="en"><p>39а Gorky St., Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Читинская государственная медицинская академия» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>08</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>151</fpage><lpage>158</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пушкарёв Б.С., Большакова О.В., Покоева З.А., Витковский Ю.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Пушкарёв Б.С., Большакова О.В., Покоева З.А., Витковский Ю.А.</copyright-holder><copyright-holder xml:lang="en">Pushkarev B.S., Bolshakova O.V., Pokoeva Z.A., Vitkovsky Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.zabmedvestnik.ru/jour/article/view/179">https://www.zabmedvestnik.ru/jour/article/view/179</self-uri><abstract><p>В обзоре представлены современные данные о физиологической роли рианодиновых каналов и участии их генетического полиморфизма в патогенезе сердечно-сосудистых заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>The review contains up-to-date data on the physiological role of ryanodine channels and the involvement of their genetic polymorphism in the pathogenesis of cardiovascular diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рианодиновые каналы</kwd><kwd>RyR2</kwd><kwd>сердце</kwd><kwd>сосуды</kwd><kwd>гладкая мускулатура сосудов</kwd><kwd>мышечное сокращение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ryanodine channels</kwd><kwd>RyR2</kwd><kwd>heart</kwd><kwd>vessels</kwd><kwd>vascular smooth muscle</kwd><kwd>muscle contraction</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена при финансовой поддержке ФГБОУ ВО Читинская государственная медицинская академия Минздрава РФ в рамках утвержденного плана НИР.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Woll K.A., Petegem F.V. 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