zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2023_2_141zabmedvestnik-178Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSРИСК РАЗВИТИЯ БРОНХИАЛЬНОЙ АСТМЫ У ДЕТЕЙ, ПЕРЕНЁСШИХ РЕСПИРАТОРНО-СИНЦИТИАЛЬНУЮ ИНФЕКЦИЮ В РАННЕМ ВОЗРАСТЕTHE RISK OF DEVELOPING ASTHMA IN CHILDREN, WHO HAVE HAD RESPIRATORY SYNCYTIAL INFECTION IN INFANCYМедведеваА. С.MedvedevaA. S.

672000, г. Чита, ул. Горького, 39А 

39a Gorky Street, Chita, 672000  

ЩербакВ. А.ShcherbakV. A.

672000, г. Чита, ул. Горького, 39А 

39a Gorky Street, Chita, 672000  

Федеральное государственное бюджетное учреждение высшего образования «Читинская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияChita State Medical AcademyRussian Federation20230508202402141150Copyright © Медведева А.С., Щербак В.А., 20242024Медведева А.С., Щербак В.А.Medvedeva A.S., Shcherbak V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/178

Причины формирования бронхиальной астмы (БА) по сей день являются объектом большинства исследований. Известно, что перенесенные острые респираторные заболевания, имея определённую сезонность, могут вызывать периодическое возникновение обструкций дыхательных путей с дальнейшим формированием БА, что ведёт к учащению обращений за медицинской помощью и ухудшению качества жизни.

Научный обзор посвящен обобщению результатов современных исследований по отдаленным последствиям респираторно-синцитиальной вирусной инфекции (РСВИ), перенесенной в раннем возрасте. Использованы базы данных PubMED, РИНЦ. Ключевыми словами для поиска являлись: респираторно-синцитиальная вирусная инфекция, ранний детский возраст, бронхообструктивный синдром, бронхиальная астма, паливизумаб, нирсевимаб, мотавизумаб. Обнаружено 42187 статей по поисковым словам за последние 5 лет. Большинство публикаций отмечают патогенетическую связь между РСВИ и БА. Также авторы отмечают необходимость проведения иммунизации младенцев моноклональными антителами для предотвращения развития осложнений.

The causes of the formation of bronchial asthma (BA) are the object of most research to this day. It is known that past acute respiratory diseases, having a certain seasonality, can cause periodic occurrence of airway obstruction, with the further formation of BA, which leads to an increase in requests for medical help and a deterioration in the quality of life.

The scientific review is devoted to summarizing the results of modern research on the long-term consequences of respiratory syncytial virus infection (RSVI) transferred at an early age. The databases PubMED, RSCI were used. The search keywords were: respiratory syncytial virus infection, early childhood, broncho-obstructive syndrome, bronchial asthma, palivizumab, nirsevimab, motavizumab. Found 42187 publications for search words over the past 5 years. Most publications note a pathogenetic relationship between RSVI and BA. The authors also note the need for immunization of infants with monoclonal antibodies to prevent the development of complications.

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The authors declare that there are no conflicts of interest present.