zabmedvestnikЗабайкальский медицинский вестникTransbaikalian Medical Bulletin1998-6173Читинская государственная медицинская академия10.52485/19986173_2022_2_91zabmedvestnik-167Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSПОТЕНЦИАЛ-ЗАВИСИМЫЕ КАЛИЕВЫЕ КАНАЛЫ KV7.1 (KCNQ1): ФИЗИОЛОГИЧЕСКОЕ ЗНАЧЕНИЕ И СВЯЗАННАЯ ПАТОЛОГИЯVOLTAGE-GATED POTASSIUM CHANNELS KV7.1 (KCNQ1): PHYSIOLOGICAL SIGNIFICANCE AND ASSOCIATED PATHOLOGYИвановД. П.IvanovD. P.

672038, Чита, ул. Коханского, 7

7 Kokhanskogo str., Chita, 672038

ФёдороваА. П.FyodorovaA. P.

672000, Чита, ул. Горького, 39а

39a Gorky str., Chita, 672000

СеребряковаО. В.SerebryakovaO. V.

672000, Чита, ул. Горького, 39а

39a Gorky str., Chita, 672000

ГУЗ «Краевая клиническая больница», Забайкальский крайРоссияChita Regional HospitalRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Читинская государственная медицинская академия» Минздрава РоссииРоссияChita State Medical AcademyRussian Federation202205082024029198Copyright © Иванов Д.П., Фёдорова А.П., Серебрякова О.В., 20242024Иванов Д.П., Фёдорова А.П., Серебрякова О.В.Ivanov D.P., Fyodorova A.P., Serebryakova O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.zabmedvestnik.ru/jour/article/view/167

В обзоре приведены краткие сведения об истории открытия, строении и принципах функционирования потенциал-зависимого калиевого канала Kv7.1 (KCNQ1). Представлены современные данные о физиологической роли Kv7.1 в разных органах и тканях. Описаны основные патологические состояния, связанные с мутациями в гене, кодирующем Kv7.1.

This review provides information on the history of discovery, structure, and principles of functioning of the voltage-gated potassium ion channel Kv7.1 (KCNQ1). Current data on the physiological role of Kv7.1 in various organs and tissues are presented. The main pathological conditions associated with mutations in the gene encoding Kv7.1 are described.

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The authors declare that there are no conflicts of interest present.